Q: Give 5 importance of studying toxicology and how does toxicity develop
A: Toxic substance There are many substances that have the potential to produce toxic effect or injury.…
Q: Description of clinical trial process for the Pfizer-BioNTech. Incorporate the following key words:…
A: Pfizer also known as BNT162b2 mRNA covid-19 vaccine is a lipid nano-particle formulation,…
Q: Explain the role of toxicological parameters ED50 in ensuring the safety of a drug candidate.…
A: Toxicological parameters - It is the level of toxicity to determine drug usage. The toxicological…
Q: evaluation of crude drugs
A: Crude drugs are obtained from any parts of the plants and consist of one or more active ingredients…
Q: What are tetra amino macrocyclic lignands and their role in environmental toxicology
A: TAMLs is abbreviated as tetra-amido macrocyclic ligands. These are used for the degradation of…
Q: the concept of dose-response related to the following statement by Paracelsus: “All substances are…
A: Although some chemicals, such as arsenic compounds, are generally recognised as poisons, many people…
Q: The dose-response effect is best described as A. when the value of the response variable changes…
A: The dose-response relationship, or exposure-response relationship, defines the magnitude of an…
Q: AET is called differently in European Pharmacopeia and Japanese Pharmacopeia, what are these names?
A: Pharmacopeia is a bok that describes various chemicals, drugs, and medicinal preparations according…
Q: The concept of hierarchy of control describes the order of effectives of mitigation measure. The…
A: The assumption behind this hierarchy of control is that the control measures at the top are likely…
Q: The beneficial impact of food additives outweighs the harmful impact. To what extent do you agree or…
A: Food additives are substances that are added to food to retain or improve the flavor, enhance the…
Q: Discuss controlled release technology and its significance for the maintenance of constant drug…
A: The controlled drug release has been in experimentation for 50 years. The latest technologies have…
Q: "MSG" is an abbreviation for a food additive; what is the indicate? and why is it not advised for…
A: A small number of certain chemicals are added in food processing, these substances are called food…
Q: Antimicrobial Effectiveness Tesct (AET) is called differently in European Pharmacopeia and…
A: Answer : In Antimicrobial Effectiveness Test(AET) is called differently in European Pharmacopeia is…
Q: Which of the following is a useful pharmacokinetic parameter that provides an accurate indication of…
A: Pharmacokinetics means In this branch of medicine science consider the absorption , metabolism,…
Q: In the dose response curve below, Drug B has [ Select ] * potency and [ Select ] efficacy as Drug A
A: Efficacy and potency are two characteristic features of a drug, which shows how effective and potent…
Q: Why are the four main topics of ecological risk analysis important to risk assessment
A: Ecological Risk Assessment is the process of determining the dangers presented by substances…
Q: What is the importance of the specialist in the analysis of the results obtained by QSAR models of…
A: A specialist is a person that specializes in a particular field of study or are experts in their…
Q: What is OECD Guidelines in toxicology or toxicity studies? How does it work and its purpose?
A: The OECD (Organisation for Economic Cooperation and Development) has created a series of guidelines…
Q: describe and cite a simple yet practical example on how the Lean Six Sigma can be applied in…
A: Lean Six Sigma is the method relying on the effort of a collaborative team to improve performance by…
Q: resistance
A: Answer: true
Q: would a dose-response relationship affects toxicity?
A: If dose response curve is steep then toxic dose of drug will also be less.( Toxicity due to action…
Q: A drug with the lower ED50 value is the more effective drug. false true
A: A drug’s efficacy is tested in vitro and in vivo as well. Its different dose levels are assessed to…
Q: What is asthma? Describe, symptoms, causes, treatment options. What could you do to provide a safe…
A: Hello, as your question has many parts, we will only answer the first three parts for you and if you…
Q: what particular group of people does Candian public health association (CPHA) serves?
A: Canadian public health association is a a non government association which deals with public health…
Q: What is the off label use of Isoniazid medicine ?
A: In adults and adolescents with human immunodeficiency virus (HIV), the prescribed dose of isoniazid…
Q: Pick a pathogen, suggest tests that should be performed on that pathogen to determine the specific…
A: In a living organism, infection tends to occur with invasion, growth, and reproduction of…
Q: FTE Formula:Number of encountersProductivity rateThe HIM department is transitioning to electronic…
A: FTE (Full-Time Equivalent) is the indicator of the workload of an employee. It is calculated by…
Q: What is the key to the greater success in all forms of exposure treatment ?
A: The therapies that are used to treat mental health disorders are collectively represented as…
Q: What is the history of toxicology during the 20 th century and the 21 st century? Who were the…
A: Toxicology is a discipline of science concerned with the effects and treatment of toxins and…
Q: Which of these dispensing practices are CORRECT?
A: The condition in which arises due to acute illness or injury that may be an immediate risk to an…
Q: Discuss the toxicological effects of un-intentional by-product on plant, animals and human being?
A: Hexachlorobenzene (HCB) was used as a seed-dressing for crops to stop fungal illness. it's used as…
Q: A toxin with a higher LD50 value is more deadly than a toxin with a lower LD50 value, assuming a…
A: LD50 value Median lethal dose is a measure of lethal dose of a toxic chemical.
Q: What are the different methods of drug administrations? How to do the methods of drug…
A: A drug is an active chemical entity that is present in medicine and that can be used for either…
Q: The predetermined Quality Adjusted Life Year (QALY) cost in Canada is S100,000 A 40 year old, who is…
A: Introduction- The quality adjusted life year (QALY) gives us the guidance in giving the alternative…
Q: Discuss the effects of these products on the planet and the population. Please address all three…
A: Human beings use a large number of chemicals in their everyday life. Chemicals are an integral part…
Q: Choose the correct one, Which is the useful pharmacokinetic parameter that provides an accurate…
A: Many of the factors are mainly responsible for influencing drug efficacy. One such important factor…
Q: What are TAMLs? Describe their role in environmental Toxicology
A: Environmental toxicology is the branch of science that deals with the harmful effects of various…
Q: Check the curve below and explain in details and using your own words this dose response…
A: *The graph, Risk of dying or mortality on y-axis. Dose of drinks per day on x-axis *Represents…
Q: Why are animals used in laboratory experiments in toxicology? Explain the dose-response curve. Why…
A: Animals have typically been utilised in scientific tests to avoid ethical quandaries associated with…
Q: A 40 years old patient is admitted to the hospital with numerous pus cells in urine and leg swelling…
A: ACE (angiotensin-converting enzyme) inhibitors inhibit the conversion of angiotensin-II from…
Q: Which of the following is not true about the premise of a dose/response relationship? A There is a…
A: Disclaimer: According to the guidelines of Bartleby, I am solving only the first question. Please…
Q: While running for a charity race marathon, Nurse Baby Boy noted that he ran out of water for…
A: This situation is dangerous because he can fall into dehydration.Dehydration is a deficiency in…
Q: Therapeutic intensity tells something about the drug burden in a population. How is therapeutic…
A: Therapeutic intensity defines the drug burden index of a drug being used. The Drug Burden Index…
Q: How to minimize the response flactuation from levodopa therapy? Please answer at your own easy…
A: Levodopa therapy is used to treat patients with Parkinson's disease. It is a disease in which…
Q: different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring the…
A: Toxicology helps us to understand the harmful effects of the chemicals, on the people and…
Q: Discuss the study of chemical hazards and their effects,including wildlife toxicology, epidemiology,…
A: Toxicants can be both organic and manmade, and there are hundreds of synthetic compounds in our…
Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…
A: In the development of new drug it is very important to make sure about its safety. After the invitro…
Q: Discuss the following briefly based on your understanding. 1. Incubation period 2. Deworming 3.…
A: Microorganisms should be cultivated in environments that promote their growth, such as the right…
Q: . characterize the physical-chemical properties of environmental contaminants related to their…
A: Environmental contaminants are chemicals that accidentally enter the environment as a result of…
- What knowledge can be gained from dose-response relationships?
- Why are the shape and slope of a dose-response curve important?
What role do shape and slope play in environmental toxicology?
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
- A quantal dose response data was collected for Drug A to determine ED50. The total number of subjects tested was 100. The equation of the linear portion of the quantal dose-response curve was determined to be y = 0.2316x - 14.337. Calculate the ED50 value for Drug A. Group of answer choices 278 529 420 350Prepare a memory card that lists the basic metric units of measurement and common equivalent measures for conversion from one system to another. Prepare a poster that depicts how to multiply and divide common fractions to calculate drug dosages. Prepare a comparative chart listing the abbreviations, symbols, and features of the following three systems of measurement in healthcare: • Household measurement system • Apothecary system • Metric systemThe high dosing of a medication to quickly achieve a therapeutic level is known as effective dose, loading dose, or maintenance dose?
- a) Define EDso and TDso. Calculate the therapeutic index (TI) for each of the following drugs based on the dose-response curves provided. Comment on the safety of these two treatments. 100 80- 60- 40- 20- Drug 1 Therapeutic effect Toxic effect 100 200 300 400 500 600 700 Drug dose (mg) 100- Therapeutic effect 80- 60- 17 40- 20- 0- 10 20 Drug 2 40 Toxic effect 60 80 100 120 Drug dose (mg) 140"LD50" refers to the median "lethal dose," which is the concentration at which 50% of the population would die. Toxicologists also use dose-response curves to determine the median "toxic dose," or TD50. This is the dose required to cause a specific response or symptom (such as loss of hearing or headaches) for 50% the population. 100- 50 0 Linear dose-response curve. Low (a) Linear dose-response curve Dose LD 50 Copyright 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings → High 12. Approximately what is the threshold dose for the toxicant shown in the graph to the right? Adanted from 1 Nauran 13. What is the LD50 for the toxicant shown in the graph to the right? 100- 50- 0 Low (weaver) asoodsad Linear dose-response curve. Dose (b) Dose-response curve with threshold As shown in the graphs above, if the response begins at any dose and increases continuously as dosage increases, then it is referred to as a non-threshold response curve. However, if the response does not…Read the following scientific paper from J.K Aronson titled: Medication errors: what they are, how they happen, and how to avoid them QJM: An International Journal of Medicine, Volume 102, Issue 8, August 2009, Pages 513– 521, https://doi.org/10.1093/qjmed/hcp052 Focus on the following sections: Abstract One particular medication error Frequency and outcomes of medication errors Conclusion: a prescription for better prescribing Once you have done the reading: Prepare a 150-200 words reflection piece on the importance of Topic 1 measurements for future health care professionals as you. Base your reflection on the resources provided. Drug Dosage and Body mass Medication errors: what they are, how they happen, and how to avoid them) You are most welcome to do quick research on measurement errors in your desired field of practice too (Pharmacy, Paramedic, Nutrition, Health Science, Exercise Science, Physiotherapy etc). To help you out here are some questions to answer in your…
- What is a prototype? What is an indication? A contraindication? What is the number one contraindication to any medication? Difference between primary and secondary effects of a drug? What is the active ingredient? What does the active ingredient in a drug do? Inert ingredients? What is the difference between an adverse effect and an adverse drug event and an adverse drug reaction? What is the difference between subjective and objective data What are the parts of a patient’s drug profile? Additive effect, what is it? Cummulative effect? Synergistic effect? Iatrogenic effects? Antagonistic effect? How do antagonists work at the receptors? What is an idiosyncratic response? Teratogenic effect? Allergic response? What does the nurse do in each phase of the Nursing Process when administering medications? Agonist effect? How do agonists work? Antagonists? What is a general property of how drugs work? What can drugs cause to happen and what can drugs NOT CAUSE to happen in the body? Why…There are two special populations that require extra consideration when you are calculating medication dosages. These are pediatric (children) and geriatric (mature adult) patients. Generally speaking, pediatric patients are under the age of 18, and geriatric patients are 65 and over. Explain the factors impacting dosing and medication administration to these patients. Additionally, explain how a patient's weight influences their dosage.FTE Formula:Number of encountersProductivity rateThe HIM department is transitioning to electronic records. The process involves scanning 7500 inpatient records, 3000 outpatient records and 2500 emergency records. The hospital estimates there are 30 pages per inpatient record, 4 pages per outpatient record, and 4 pages per emergency record. One scanning clerk can scan 7500 pages per day...The HIM department would like to complete this project in 10 days. How many FTEs will the HIM department need to hire to complete this in the desired time frame?
- Which statements regarding the preclinical research stage of drug development are true? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply. Group of answer choices Most drugs do not proceed past the preclinical stage because they are found to be too toxic or just ineffective. Client variability is determined and potential drug—drug interactions are examined during pre-clinical testing.. The preclinical stage of research involves extensive testing on animals in the laboratory to determine if the drug will cause harm to humans. The Food and Drug Administration (FDA) is responsible for extensive testing for safety before the pharmaceutical company can begin the preclinical research stage of development.What are the different component of therapeutic index. Define its clinical relevancePick a pathogen, suggest tests that should be performed on that pathogen to determine the specific drugs and give reasons why they would be appropriate. (Terminology to incorporate: narrow-spectrum, broad-spectrum, MIC, Kirby-Bauer, therapeutic index, selective toxicity, drug mechanism)