What is Wolf's law?
The current intellectual front end of systems biology is the search for basic organizing principles. Organisms manage massively parallel and massively interacting processes over multiple orders of magnitude in size, from a hydrogen atom to the whole-cell level. It is normal to expect organizing principles that define higher-order behavior to manage this magnitude of informational complexity. There are just suggestions of such organizing principles at the moment, but no concrete evidence. The method entails identifying constants at different levels and weaving them into a hierarchical framework. Our grasp of the underlying principles in biology will increase as we find and arrange constants, from pair-wise interactions to networks, ultimately to a theory in biology.
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