What is the ratio of benzaldehyde to thiamine hydrochloride used in this reaction? Why are we not using a full equivalent of this reagent?

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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What is the ratio of benzaldehyde to thiamine hydrochloride used in this reaction? Why are we not using a full equivalent of this reagent? 

STEP-1: SYNTHESIS OF BENZOIN (IV-01)
CHO
ОН
Ph
Thiamine HCI
Ph
NaOH (aq)
IV-01
Add thiamine hydrochloride (750 mg) to a suitable round bottom flask. Dissolve the solid
in water (2.5 mL) by swirling, add 95% ethanol (2.5 mL) and cool the solution for a few
minutes in an ice bath. Place a stir bar in the flask and, with stirring, add 2.5 mL of 2M
NaOH. Add benzaldehyde (44 mmol) dissolved in 3 mL of 95% ethanol.
Transcribed Image Text:STEP-1: SYNTHESIS OF BENZOIN (IV-01) CHO ОН Ph Thiamine HCI Ph NaOH (aq) IV-01 Add thiamine hydrochloride (750 mg) to a suitable round bottom flask. Dissolve the solid in water (2.5 mL) by swirling, add 95% ethanol (2.5 mL) and cool the solution for a few minutes in an ice bath. Place a stir bar in the flask and, with stirring, add 2.5 mL of 2M NaOH. Add benzaldehyde (44 mmol) dissolved in 3 mL of 95% ethanol.
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