What is the major product of the following reaction? Note that the reaction is run in THF, an aprotic solvent. (Hint 1: Typically reductions with borohydride are run in protic solvents. What is the role of that protic solvent in those cases. How does the aprotic solvent change things here?) (Hint 2: Keeping Hint 1 in mind, write the mechanism! At each step ask "what can happen next?") OTS NaBH4 THF ?

What is the major product of the following reaction? Note that the reaction is run in THF, an aprotic solvent. (Hint 1: Typically reductions with borohydride are run in protic solvents. What is the role of that protic solvent in those cases. How does the aprotic solvent change things here?) (Hint 2: Keeping Hint 1 in mind, write the mechanism! At each step ask "what can happen next?") OTS NaBH4 THF ?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

What is the major product of the following reaction? Note that the reaction is run in THF, an aprotic solvent.
(Hint 1: Typically reductions with borohydride are run in protic solvents. What is the role of that protic solvent
in those cases. How does the aprotic solvent change things here?)
(Hint 2: Keeping Hint 1 in mind, write the mechanism! At each step ask "what can happen next?")
O A
ο ο ο ο
U
O B
(A)
(B)
OTS
NaBH4
THF
?
OH H
(C)
fo
(D)

What is the major product of the reaction below?
(A)
O A
O
O
O
U
OH
(B)
1) excess LiAlH4
2) H₂O
HO
(C)
?
OH
е он
(D)

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