What is the interactome?
The branch of biology that deals with the study of the composition, structure and interactions of cellular molecules such as nucleic acids and proteins, that carry out the essential biological processes essential for the maintenance of cell's functions.
The term "interactome" was coined by a group of French scientists headed by Bernard Jacq in 1999.
An interactome refers to the whole set of molecular interactions in a specific cell. The term interactome, particularly refers to physical interactions among molecules but can also describe sets of indirect interactions among genes.
An interactome network refers to all the protein-protein interactions which occurs in a cell. These interactome maps have been created for yeast, worms and flies. The interactome based on protein-protein interactions must be related to the proteome, that is entire set of proteins, of the corresponding species in order to deliver a global vision of all the possible molecular interactions that a protein can present.
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