What is the distinguishing feature of a case-control study such as this? In a recent case-control study, investigators enrolled 300 adults with heart disease and 300 healthy adults. During interviews with the participants, the investigators determined participants' use of multivitamins in childhood, which was dichotomized into yes or no. The exposure and outcome were measured at the same time, so temporality cannot be established. Participants were selected based on disease status, and then exposure status was assessed from the past. The investigator randomized participants into exposure groups and then followed them to see who developed the outcome. Exposure status was assessed, and then the participants were followed up over time to see who developed the outcome.

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6.
**What is the distinguishing feature of a case-control study such as this?**

In a recent case-control study, investigators enrolled 300 adults with heart disease and 300 healthy adults. During interviews with the participants, the investigators determined participants’ use of multivitamins in childhood, which was dichotomized into yes or no.

- ○ The exposure and outcome were measured at the same time, so temporality cannot be established.

- ○ Participants were selected based on disease status, and then exposure status was assessed from the past.

- ○ The investigator randomized participants into exposure groups and then followed them to see who developed the outcome.

- ○ Exposure status was assessed, and then the participants were followed up over time to see who developed the outcome.
Transcribed Image Text:**What is the distinguishing feature of a case-control study such as this?** In a recent case-control study, investigators enrolled 300 adults with heart disease and 300 healthy adults. During interviews with the participants, the investigators determined participants’ use of multivitamins in childhood, which was dichotomized into yes or no. - ○ The exposure and outcome were measured at the same time, so temporality cannot be established. - ○ Participants were selected based on disease status, and then exposure status was assessed from the past. - ○ The investigator randomized participants into exposure groups and then followed them to see who developed the outcome. - ○ Exposure status was assessed, and then the participants were followed up over time to see who developed the outcome.
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