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What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?

What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?

Phlebotomy Essentials
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
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What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?

Based on the table below, what would be the recommended dosage of "Levofloxacin 500 mg IV every 24 hours" if the 72-year-old patient weight is 78 kg and has a serum creatinine: 3.2 mg/dL?

 

 

Dose regimen 250 mg/24 h 500 mg/24 h 500 mg/12 h Creatinine clearance first dose: 250 mg first dose: 500 mg first dose: 500 mg 50 - 20 ml/min then: 125 mg/24 h then: 250 mg/24 h then: 250 mg/12 h 19-10 ml/min then: 125 mg/48 h then: 125 mg/24 h then: 125 mg/12 h < 10 ml/min (including haemodialysis and CAPD) then: 125 mg/48 h then: 125 mg/24 h then: 125 mg/24 h 1 1No additional doses are required after haemodialysis or continuous ambulatory peritoneal dialysis (CAPD).
Transcribed Image Text:Dose regimen 250 mg/24 h 500 mg/24 h 500 mg/12 h Creatinine clearance first dose: 250 mg first dose: 500 mg first dose: 500 mg 50 - 20 ml/min then: 125 mg/24 h then: 250 mg/24 h then: 250 mg/12 h 19-10 ml/min then: 125 mg/48 h then: 125 mg/24 h then: 125 mg/12 h < 10 ml/min (including haemodialysis and CAPD) then: 125 mg/48 h then: 125 mg/24 h then: 125 mg/24 h 1 1No additional doses are required after haemodialysis or continuous ambulatory peritoneal dialysis (CAPD).
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