What is the best rationale for the difference in acidity in a 2,2-difluoro isomer and a 3,3-difluoro isomer. A. The more acidic compound has a hydrogen attached to a more electronegative atom B.The more acidic compound has a hydrogen attached to a larger atomic radius atom C. The more acidic compound has a more stable conjugate base because of addition resonance structures stabilizing the charge D. The more acidic compound has a stronger molecular dipole that increases the polarization of the acidic hydrogen E. The more acidic compound has a greater amount of s-character in the acidic bond.

Organic Chemistry: A Guided Inquiry
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ISBN:9780618974122
Author:Andrei Straumanis
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Chapter4: Polar Bonds, Polar Reactions
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Problem 28E: The following are equivalent ways of asking about the acidity of an H atom: • What is the most...
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What is the best rationale for the difference in acidity in a 2,2-difluoro isomer and a 3,3-difluoro isomer.

A. The more acidic compound has a hydrogen attached to a more electronegative atom

B.The more acidic compound has a hydrogen attached to a larger atomic radius atom

C. The more acidic compound has a more stable conjugate base because of addition resonance structures stabilizing the charge

D. The more acidic compound has a stronger molecular dipole that increases the polarization of the acidic hydrogen

E. The more acidic compound has a greater amount of s-character in the acidic bond.

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