What happens to the axon potential that arrives at the sarcolemma? B. What happens once the action potential arrives at the terminal cisternae of sarcoplasmic recticulum? C. What happens once calcium ions are released into the sarcoplasm?

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Chapter1: The Human Body: An Orientation
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A. What happens to the axon potential that arrives at the sarcolemma?

B. What happens once the action potential arrives at the terminal cisternae of sarcoplasmic recticulum?

C. What happens once calcium ions are released into the sarcoplasm?

2. Excitation-Contraction Coupling: (answer in your own words)
A
B
C'
Transcribed Image Text:2. Excitation-Contraction Coupling: (answer in your own words) A B C'
EXCITATION-CONTRACTION COUPLING
• Excitation-contraction coupling: Link between generation of action potential in
sarcolemma and start of muscle contraction. Occurs at triads.
Neural control: SMF contracts when stimulated by motor
neuron at NMJ in form of action potential at axon terminal of
Axen terminal
a neuron
Exeitation
Exeitatien
Sarcolemma
Excitation: Action potential release ACh into synaptic cleft
and produce an action potential across sarcolemma
Release of Ca2+ Action potential travels along
sarcolemma >T tubules >triads and triggers release of
Ca2+ from terminal cisternae of SR
Contraction Cycle Begins: Ca2+ bind to troponin and
exposes active sites on thin filaments for myosin to bind,
cross-bridge formation, and will continue as long as ATP is
Ttubule
Cytosol
Sarcoplasmie retioulum
Calcium
lon release
ATP
around.
Thick-thin
Slament interaetion
Sarcomere
shortening takes
place, and generation
of muscle tension on
Ca
Myosin tail
(thick filament)
Muscle fiber
contraction
Tropomyosin
Cross-bridge
formation
Troponin
leads to
Ca
G-actin
(thin filament)
tendons at either end
Ca
Nebulin
of muscles result in a
Active site
contraction
Tension
production
Transcribed Image Text:EXCITATION-CONTRACTION COUPLING • Excitation-contraction coupling: Link between generation of action potential in sarcolemma and start of muscle contraction. Occurs at triads. Neural control: SMF contracts when stimulated by motor neuron at NMJ in form of action potential at axon terminal of Axen terminal a neuron Exeitation Exeitatien Sarcolemma Excitation: Action potential release ACh into synaptic cleft and produce an action potential across sarcolemma Release of Ca2+ Action potential travels along sarcolemma >T tubules >triads and triggers release of Ca2+ from terminal cisternae of SR Contraction Cycle Begins: Ca2+ bind to troponin and exposes active sites on thin filaments for myosin to bind, cross-bridge formation, and will continue as long as ATP is Ttubule Cytosol Sarcoplasmie retioulum Calcium lon release ATP around. Thick-thin Slament interaetion Sarcomere shortening takes place, and generation of muscle tension on Ca Myosin tail (thick filament) Muscle fiber contraction Tropomyosin Cross-bridge formation Troponin leads to Ca G-actin (thin filament) tendons at either end Ca Nebulin of muscles result in a Active site contraction Tension production
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