What controls the transcription of a gene? Especially the initiation of it. i. Chromatin, histones, presence of TF, third dimensional structure…
What controls the transcription of a gene? Especially the initiation of it. i. Chromatin, histones, presence of TF, third dimensional structure…
Transcription is the first step in gene expression. It involves copying a gene's DNA sequence to make a RNA molecule.
The expression of eukaryotic genes is controlled primarily at the level of initiation of transcription, although in some cases transcription may be attenuated and regulated at subsequent steps. Transcription factors (TFs) and histone modifications (HMs) play critical roles in gene expression by regulating mRNA transcription. In addition, the packaging of DNA into chromatin and its modification by methylation impart further levels of complexity to the control of eukaryotic gene expression.
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