What carbonyl compound and Grignard reagent could be used to prepare 2-butanol?

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**Title: Preparing 2-Butanol: Selection of Carbonyl Compounds and Grignard Reagents**

**Text:**
In the context of organic synthesis, specifically the preparation of 2-Butanol, we assess the suitable combinations of carbonyl compounds and Grignard reagents. The following options are provided:

**Question:**
Which carbonyl compound and Grignard reagent can be used to prepare 2-Butanol?

**Options:**
1. CH₃CHO / CH₃CH₂CH₂MgBr
2. CH₃CH₂CHO / CH₃MgBr 
3. CH₃COCH₃ / CH₃MgBr

**Answer Choices:**
- ⃝ only I
- ⃝ only III
- ⃝ only I and II
- ⃝ only II

Give consideration to the fact that 2-Butanol can be synthesized using an aldehyde or a ketone, followed by the addition of the appropriate Grignard reagent. Study the structural formulas and the respective reagents to determine the correct combination. 

For an explanation of each option:
1. **Option I**: CH₃CHO (Acetaldehyde) with CH₃CH₂CH₂MgBr (Propylmagnesium bromide).
2. **Option II**: CH₃CH₂CHO (Propionaldehyde) with CH₃MgBr (Methylmagnesium bromide).
3. **Option III**: CH₃COCH₃ (Acetone) with CH₃MgBr (Methylmagnesium bromide).

Evaluate which reactions would yield 2-Butanol, considering that the Grignard reaction proceeds by nucleophilic addition of the Grignard reagent to the carbonyl group to form the desired alcohol.

**Note:** There are no graphs or diagrams accompanying this question. The provided information is in text format only, displayed above a MacBook Air keyboard.
Transcribed Image Text:**Title: Preparing 2-Butanol: Selection of Carbonyl Compounds and Grignard Reagents** **Text:** In the context of organic synthesis, specifically the preparation of 2-Butanol, we assess the suitable combinations of carbonyl compounds and Grignard reagents. The following options are provided: **Question:** Which carbonyl compound and Grignard reagent can be used to prepare 2-Butanol? **Options:** 1. CH₃CHO / CH₃CH₂CH₂MgBr 2. CH₃CH₂CHO / CH₃MgBr 3. CH₃COCH₃ / CH₃MgBr **Answer Choices:** - ⃝ only I - ⃝ only III - ⃝ only I and II - ⃝ only II Give consideration to the fact that 2-Butanol can be synthesized using an aldehyde or a ketone, followed by the addition of the appropriate Grignard reagent. Study the structural formulas and the respective reagents to determine the correct combination. For an explanation of each option: 1. **Option I**: CH₃CHO (Acetaldehyde) with CH₃CH₂CH₂MgBr (Propylmagnesium bromide). 2. **Option II**: CH₃CH₂CHO (Propionaldehyde) with CH₃MgBr (Methylmagnesium bromide). 3. **Option III**: CH₃COCH₃ (Acetone) with CH₃MgBr (Methylmagnesium bromide). Evaluate which reactions would yield 2-Butanol, considering that the Grignard reaction proceeds by nucleophilic addition of the Grignard reagent to the carbonyl group to form the desired alcohol. **Note:** There are no graphs or diagrams accompanying this question. The provided information is in text format only, displayed above a MacBook Air keyboard.
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