what are the clinical manifestations of rheumatoid arthritis

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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what are the clinical manifestations of rheumatoid arthritis

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Step 1-Introduction

Rheumatoid arthritis (RA) is an autoimmune disorder. It is caused when the immune cells of the body mistake the cells of joints to be foreign (pathogenic) and destroy the cells. 

The joints in several areas such as fingers, shoulders, etc. are lined by synovial membranes. These membranes protect the joints from wear and tear that could occur due to rubbing, friction, etc. In RA, the immune cells attack the synovial membrane. The degradation of the synovium causes bones of the joint to rub together, which leads to bone loss/erosion, cartilage loss/erosion, and weakened bones.

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