What are the blue-gray vacuoles in the cytoplasm of the leukocytes? Is this abnormality diagnostically significant? Why or why not?

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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Read and analyze the clinical case presented below. Answer the following questions being provided.

 

A 51-year-old white man was admitted to the burn unit of a local hospital following an accident at a local foundry. Several STAT laboratory blood tests were ordered, including a complete blood count.

 

Laboratory Data:

The hemoglobin, hematocrit, and red blood cell (RBC) count were all slightly elevated. The total leukocyte count was 15.8 × 109 /L.

 

The differential count was as follows:

Band neutrophils 12%

Segmented neutrophils 65%

Lymphocytes 23%

 

Light blue-gray inclusions were observed in the cytoplasm of many of the bands and segmented neutrophils.

  1. What are the blue-gray vacuoles in the cytoplasm of the leukocytes?
  2. Is this abnormality diagnostically significant? Why or why not?
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