Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
![1. Write the synthesis of phenobarbital, give names to the initial and intermediate
substances.
2. Name the given substance. What pharmacological group does it belong to?
CH3
. H2SO4 . H20
CH2OH
3. Write the metabolism of chlordiazepoxide, name all metabolites.
4. Write the structure of benzocaine, show the fragment of primary aromatic amino
group in the structure, write the reaction for it, state the observation.
5. Write the equation for assay of acetylsalicylic acid. Give the value of stoichiometric
coefficient, formulas for the calculation of titre and percentage..](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F397c2267-3ba8-41e5-bcc3-cfb909726567%2Fd4397086-db37-43e0-b903-70c058e20937%2Fhdm6a1c_processed.jpeg&w=3840&q=75)
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