Using the information in the following graphs that show activity of phosphofructokinase (PFK) with different concentration of fructose-2,6-bisphosphate (F26BP), which of the following is true?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Using the information in the following graphs that show activity of phosphofructokinase (PFK) with
different concentration of fructose-2,6-bisphosphate (F26BP), which of the following is true?
0 L 1 μM F-2,6-BP
1 μM F-2,6-BP
80 0.1 μM
0.1 μM
0
ZE
4
5
0
1
100
Relative velocity
60
40
20
1 2 3
[Fructose 6-phosphate] (mm)
0
2
[ATP] (MM)
O ATP is an allosteric activator of PFK, F26BP is an allosteric inhibitor
ATP is an allosteric activator of PFK, F26BP is an allosteric activator
O ATP is an allosteric inhibitor of PFK, F26BP is an allosteric inhibitor
O ATP is an allosteric inhibitor of PFK, F26BP is an allosteric activator
4
5
Transcribed Image Text:Using the information in the following graphs that show activity of phosphofructokinase (PFK) with different concentration of fructose-2,6-bisphosphate (F26BP), which of the following is true? 0 L 1 μM F-2,6-BP 1 μM F-2,6-BP 80 0.1 μM 0.1 μM 0 ZE 4 5 0 1 100 Relative velocity 60 40 20 1 2 3 [Fructose 6-phosphate] (mm) 0 2 [ATP] (MM) O ATP is an allosteric activator of PFK, F26BP is an allosteric inhibitor ATP is an allosteric activator of PFK, F26BP is an allosteric activator O ATP is an allosteric inhibitor of PFK, F26BP is an allosteric inhibitor O ATP is an allosteric inhibitor of PFK, F26BP is an allosteric activator 4 5
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