Answered: Using the diagram below describe the…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Using the diagram below describe the significance of DNA sequencing for identification of mutations.

Transcribed Image Text:**Gene Characterization Approaches** **Cloning and Analyzing Genes in Biological Research** 1. **Mutation with Observable Phenotype (Model Organism or Human)** - *Input*: Mutation with an observable phenotype. - *Output*: Gene inactivation leads to a mutant phenotype. 2. **Genomic Sequence with Homology to Known Function** - *Input*: Genomic sequence with known function homolog. - *Output*: Function deduced from sequence analysis. 3. **Protein with Observable Biochemical Activity** - *Input*: Protein with observable biochemical activity. - *Output*: Protein production for biochemical activity and structure determination. Once a **cloned gene/DNA sequence** is obtained, it can be analyzed through the following processes: 1. **Expression Profile and Cellular Localization** - *Output*: Expression profile and cellular localization data. This diagram, adapted from Lodish et al., *Molecular Cell Biology, 9e*, illustrates different inputs and outputs related to cloned gene/DNA sequence analysis. Each category directs researchers to obtain specific information about gene function, expression, and structural characteristics. This structured approach is vital for understanding gene roles in biological processes. **Reference:** Lodish et al., Molecular Cell Biology, 9e, © 2021 W. H. Freeman and Company

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