use the Wilcoxon rank-sum test. Clinical Trials of Lipitor The sample data below are changes in LDL cholesterol levels in clinical trials of Lipitor (atorvastatin). It was claimed that Lipitor had an effect on LDL cholesterol. (The data are based on results given in a Parke-Davis memo from David G. Orloff, M.D., the medical team leader for clinical trials of Lipitor. Pfizer declined to provide die author with the original data values.) Negative values represent decreases in LDL cholesterol. Use a 0.05 significance level to test the claim that for those treated with 20 mg of atorvastatin and those treated widi 80 mg of atorvastatin, changes in LDL cholesterol have the same median. What do the results suggest? Group treated with 20 mg of atorvastatin: −28 −32 −29 −39 −31 −35 −25 −36 −35 −26 −29 −34 −30 Group treated with 80 mg of atorvastatin: −42 −41 −38 −42 −41 −41 −40 −44 −32 −37 −41 −37 −34 −31
use the Wilcoxon rank-sum test.
Clinical Trials of Lipitor The sample data below are changes in LDL cholesterol levels in clinical trials of Lipitor (atorvastatin). It was claimed that Lipitor had an effect on LDL cholesterol. (The data are based on results given in a Parke-Davis memo from David G. Orloff, M.D., the medical team leader for clinical trials of Lipitor. Pfizer declined to provide die author with the original data values.) Negative values represent decreases in LDL cholesterol. Use a 0.05 significance level to test the claim that for those treated with 20 mg of atorvastatin and those treated widi 80 mg of atorvastatin, changes in LDL cholesterol have the same
Group treated with 20 mg of atorvastatin:
−28 −32 −29 −39 −31 −35 −25 −36 −35 −26 −29 −34 −30
Group treated with 80 mg of atorvastatin:
−42 −41 −38 −42 −41 −41 −40 −44 −32 −37 −41 −37 −34 −31
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