True or False

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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True or False

1. Transcription has three successive phases of termination, elongation, and initiation.
2. The enzyme RNA polymerase catalyzes transcription.
3. Initiators are specialized DNA sequences near the beginning of a gene where
transcription will start.
4. All promoters in E. coli contain two characteristic short sequences of 6-10
nucleotide pairs that help bind RNA polymerase.
5. When the RNA polymerase releases the o subunit. This release marks the end of
initiation.
6. The region of DNA unwound by RNA polymerase is called the transcription bubble.
7. Once an RNA polymerase has moved off the promoter, other RNA polymerase
molecules can move in to initiate translation.
8. You started at the 5' end of a gene at point A and moved along the gene in the same
direction as RNA polymerase to point B, you would be traveling in the upstream
direction.
9. You started at point B and moved in the opposite direction to point A, you would be
traveling in the downstream direction.
10. Intrinsic terminators cause the RNA polymerase core enzyme to terminate
transcription on its own.
Transcribed Image Text:1. Transcription has three successive phases of termination, elongation, and initiation. 2. The enzyme RNA polymerase catalyzes transcription. 3. Initiators are specialized DNA sequences near the beginning of a gene where transcription will start. 4. All promoters in E. coli contain two characteristic short sequences of 6-10 nucleotide pairs that help bind RNA polymerase. 5. When the RNA polymerase releases the o subunit. This release marks the end of initiation. 6. The region of DNA unwound by RNA polymerase is called the transcription bubble. 7. Once an RNA polymerase has moved off the promoter, other RNA polymerase molecules can move in to initiate translation. 8. You started at the 5' end of a gene at point A and moved along the gene in the same direction as RNA polymerase to point B, you would be traveling in the upstream direction. 9. You started at point B and moved in the opposite direction to point A, you would be traveling in the downstream direction. 10. Intrinsic terminators cause the RNA polymerase core enzyme to terminate transcription on its own.
11. Initiators often form hairpin loops in which nucleotides within the mRNA pair with
nearby complementary nucleotides.
12. Mature messenger RNA and sequences grounded in both a gene's DNA are introns.
13. A ribonuclease recognizes AAUAAA in a particular context of the primary transcript.
14. Females typically are carriers of the DMD gene while males are affected.
15. Introns do encode polypeptides and do appear in mature mRNAS.
16. Three types of short sequences within the primary transcript-splice donors, splice
acceptors, and branch sites-help ensure the specificity of splicing.
17. The steps that involve complementary base pairing is the second step in which the
nucleotide is linked in complementarity with the DNA template.
18. The degeneracy of the genetic code restricts the effects of error made in
transcription.
19. Errors in transcription can lead to silent mutations encoding the same amino acid or
an altered protein that retains its functionality.
20. Trans-splicing is when spliceosome joins an intron of one gene with an intron of
another gene.
Transcribed Image Text:11. Initiators often form hairpin loops in which nucleotides within the mRNA pair with nearby complementary nucleotides. 12. Mature messenger RNA and sequences grounded in both a gene's DNA are introns. 13. A ribonuclease recognizes AAUAAA in a particular context of the primary transcript. 14. Females typically are carriers of the DMD gene while males are affected. 15. Introns do encode polypeptides and do appear in mature mRNAS. 16. Three types of short sequences within the primary transcript-splice donors, splice acceptors, and branch sites-help ensure the specificity of splicing. 17. The steps that involve complementary base pairing is the second step in which the nucleotide is linked in complementarity with the DNA template. 18. The degeneracy of the genetic code restricts the effects of error made in transcription. 19. Errors in transcription can lead to silent mutations encoding the same amino acid or an altered protein that retains its functionality. 20. Trans-splicing is when spliceosome joins an intron of one gene with an intron of another gene.
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