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True or false:
the antigen binding site of an antibody is found in the variabe region of the antibody.
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Solved in 2 steps
- True or false: the antigen binding site of an antibody is found in the variable region of the antibody.True/False: The antibody protein has two functional domains, one for antigen binding and a second to confer specific effector functions. These two functional domains are encoded by the antibody light chain and antibody heavy chain polypeptides, respectively.True/False: The different classes of immunoglobulins differ in the sequences of their heavy chain constant regions. As a result, each class of antibody has distinct effector functions. Nonetheless, they are all found at about equal concentrations in the serum of healthy individuals.
- True or false: The variable region of an antibody may change after the antibody has been produced, in response to antigenic variation.True/False: Antibody binding to a pathogen surface is greatly enhanced when both antigen-binding sites of the antibody are engaged at once, a feature known as bivalent binding. It is possible for antibodies to bind bivalently to a wide variety of components on many different pathogen surfaces due to the flexibility in the protein at the hinge region and at the V–C junction.True or False: The most abundant type of antibody, IgG, is the first to respond to an invading pathogen?
- True or False: A person develops anti-A antibodies only after he is exposed to antigen A, and anti-B antibodies only after he is exposed to antigen B.True or False: In complement fixation, a positive test result means that the red blood cells used in the test are destroyedAntibodies designed to interact with a specific antigensite are (monoclonal, polyclonal).
- On an antibody the variable regions form the __________________.Whether the statement, "Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made." is true or false.True/False: Like innate sensors of infections (TLRs, NLRs, RLRs), antibodies frequently recognize nucleic acids of pathogenic organisms