Trace the pathway of [14C]bicarbonate through gluconeogenesis. Use an asterisk to indicate the location of ¹4C in all intermediates and in the final gluconeogenesis product, glucose.
Trace the pathway of [14C]bicarbonate through gluconeogenesis. Use an asterisk to indicate the location of ¹4C in all intermediates and in the final gluconeogenesis product, glucose.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
![Trace the pathway of [14C]bicarbonate through gluconeogenesis. Use an asterisk to indicate the location of ¹4C in all
intermediates and in the final gluconeogenesis product, glucose.
HO-C
O-
=0
[¹C] Bicarbonate
CH₂OPO
H-C-OH
--OPO
O
1,3-Bisphospho-
glycerate
↑
-COO
-CH₂
TC=O
coo
Oxaloacetate
CH,OPO
H-C-OH
COO
↑
3-Phosphoglycerate
CH₂
C-OPO
-COO
Phosphoenolpyruvate
CH,OH
HC-OPO,
COO
2-Phosphoglycerate
Answer Bank](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fde4307a4-fc9b-4076-b372-5be51d1aa92e%2F3da9690c-8e65-4498-9e97-6d55aee99172%2F4kozono_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Trace the pathway of [14C]bicarbonate through gluconeogenesis. Use an asterisk to indicate the location of ¹4C in all
intermediates and in the final gluconeogenesis product, glucose.
HO-C
O-
=0
[¹C] Bicarbonate
CH₂OPO
H-C-OH
--OPO
O
1,3-Bisphospho-
glycerate
↑
-COO
-CH₂
TC=O
coo
Oxaloacetate
CH,OPO
H-C-OH
COO
↑
3-Phosphoglycerate
CH₂
C-OPO
-COO
Phosphoenolpyruvate
CH,OH
HC-OPO,
COO
2-Phosphoglycerate
Answer Bank

Transcribed Image Text:1,3-Bisphospho-
glycerate
CH₂OPO
H C-OH
-H
Glyceraldehyde
3-phosphate
3-Phosphoglycerate
CH₂OPO
(0
-CH₂OH
Dihydroxyacetone
phosphate
20,POH,C CH,OPO
HOHC
FO
HO-L-C-OH
HH
Fructose 1,6-bisphosphate
2-Phosphoglycerate
H.
HIC OH
HO-C-H
H-C-OH
H-C1OH
CH,OH
Glucose
Expert Solution
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