To determine if topiramate is an effective treatment for alcohol dependence, researchers conducted a 14-week trial of 371 men and women aged 18 to 65 years diagnosed with alcohol dependence. In this doubleblind, randomized, placebo-controlled experiment, subjects were randomly given either 300 milligrams (mg) of topiramate (183 subjects) or a placebo (188 subjects) daily, along with a weekly compliance enhancement intervention. The variable used to determine the effectiveness of the treatment was self-reported percentage of heavy drinking days. Results indicated that topiramate was more effective than placebo at reducing the percentage of heavy drinking days. The researchers concluded that topiramate is a promising treatment for alcohol dependence. Complete parts (a) through 12 (a) What does it mean for the experiment to be placebo-controlled? OA. The experiment will have a control group that takes a placebo, which is a lesser dose of the medication. This control group serves as a baseline treatment that group that is taking the full dose of the medication. OB. The experiment will have a placebo group that takes no medication. This placebo group serves as a baseline treatment that can be used medication. to compare can be used to compare to the is actually taking treatment that can be used to to the group that OC. The experiment will have a control group that takes a placebo, which is a innocuous medication, such as a sugar tablet. This control group serves compare to the group that is actually taking the medication. as a baseline

MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
Question

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To determine if topiramate is an effective treatment for alcohol dependence, researchers conducted a 14-week trial of 371 men and women aged 18 to 65 years diagnosed with alcohol dependence. In
this doubleblind, randomized, placebo-controlled experiment, subjects were randomly given either 300 milligrams (mg) of topiramate (183 subjects) or a placebo (188 subjects) daily, along with a weekly
compliance enhancement intervention. The variable used to determine the effectiveness of the treatment was self-reported percentage of heavy drinking days. Results indicated that topiramate was
more effective than placebo at reducing the percentage of heavy drinking days. The researchers concluded that topiramate is a promising treatment for alcohol dependence. Complete parts (a) through
(2)
(a) What does it mean for the experiment to be placebo-controlled?
OA. The experiment will have a control group that takes a placebo, which is a lesser dose of the medication. This control group serves as a baseline treatment that can be
group that is taking the full dose of the medication.
OB. The experiment will have a placebo group that takes no medication. This placebo group serves as a baseline treatment that can be used to compare
medication
to the group that
OC. The experiment will have a control group that takes a placebo, which is a innocuous medication, such as a sugar tablet. This control group serves as a baseline
compare to the group that is actually taking the medication.
used to compare to the
is actually taking
treatment that can be used to
Transcribed Image Text:To determine if topiramate is an effective treatment for alcohol dependence, researchers conducted a 14-week trial of 371 men and women aged 18 to 65 years diagnosed with alcohol dependence. In this doubleblind, randomized, placebo-controlled experiment, subjects were randomly given either 300 milligrams (mg) of topiramate (183 subjects) or a placebo (188 subjects) daily, along with a weekly compliance enhancement intervention. The variable used to determine the effectiveness of the treatment was self-reported percentage of heavy drinking days. Results indicated that topiramate was more effective than placebo at reducing the percentage of heavy drinking days. The researchers concluded that topiramate is a promising treatment for alcohol dependence. Complete parts (a) through (2) (a) What does it mean for the experiment to be placebo-controlled? OA. The experiment will have a control group that takes a placebo, which is a lesser dose of the medication. This control group serves as a baseline treatment that can be group that is taking the full dose of the medication. OB. The experiment will have a placebo group that takes no medication. This placebo group serves as a baseline treatment that can be used to compare medication to the group that OC. The experiment will have a control group that takes a placebo, which is a innocuous medication, such as a sugar tablet. This control group serves as a baseline compare to the group that is actually taking the medication. used to compare to the is actually taking treatment that can be used to
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