The FIGLU(N-formimino glutamate) test is used to identify deficiencies of vitamin B12 or folate. Explain the biochemistry behind excretion of FIGLU (N-formimino glutamate) in the urine of folic acid deficient individuals after ingestion of a large dose of histidine.

The FIGLU(N-formimino glutamate) test is used to identify deficiencies of vitamin B12 or folate. Explain the biochemistry behind excretion of FIGLU (N-formimino glutamate) in the urine of folic acid deficient individuals after ingestion of a large dose of histidine.

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter22: Medications Used For Gastrointestinal System Disorders

Section: Chapter Questions

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Concept explainers

Nitrogen metabolism

Nitrogen metabolism is the synthesis, utilization or uptake, breakdown, and excretion of nitrogenous compounds in the body. The nitrogen metabolism encompasses nitrogen fixation, biosynthesis, and the breakdown of amino acids, purines, and pyrimidine. Since nitrogen-containing compounds are required for various life processes, nitrogen is an important element of life.

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