The widely used anticoagulant warfarin (see "Chemical Connections: From Moldy Clover to a Blood Thinner" in Chapter 18) is synthesized from 4-hydroxycoumarin, benzaldehyde, and acetone as shown in this retrosynthesis. Show how warfarin is synthesized from these reagents. OH OH Acetone + Warfarin 4Нydroxy- (a synthetic anticoagulant; racemic) coumarin Benzaldehyde

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The widely used anticoagulant warfarin (see "Chemical Connections: From Moldy
Clover to a Blood Thinner" in Chapter 18) is synthesized from 4-hydroxycoumarin,
benzaldehyde, and acetone as shown in this retrosynthesis. Show how warfarin is
synthesized from these reagents.
OH
OH
Acetone
+
Warfarin
4Нydroxy-
(a synthetic anticoagulant;
racemic)
coumarin
Benzaldehyde
Transcribed Image Text:The widely used anticoagulant warfarin (see "Chemical Connections: From Moldy Clover to a Blood Thinner" in Chapter 18) is synthesized from 4-hydroxycoumarin, benzaldehyde, and acetone as shown in this retrosynthesis. Show how warfarin is synthesized from these reagents. OH OH Acetone + Warfarin 4Нydroxy- (a synthetic anticoagulant; racemic) coumarin Benzaldehyde
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