I need help please ### The Transmitter GABA Excites Immature Cortical Neurons Because:- ○ immature GABA receptors pass more sodium than chloride.- ○ immature GABA-receptive neurons have a more negative firing threshold than mature neurons.- ○ immature GABA-receptive neurons have a higher intracellular chloride concentration than mature neurons.- ○ immature GABA-receptive neurons express many more chloride pumps taking chloride out.- ○ the opening of GABA receptor channels tends to excite immature cortical networks because of the networks' wiring.

The question pertains to the intriguing phenomenon of how the neurotransmitter GABA (gamma-aminobutyric acid) affects immature cortical neurons. GABA is traditionally known as an inhibitory neurotransmitter, responsible for dampening neuronal excitability in the mature nervous system. However, during early developmental stages, GABA can paradoxically induce excitation in certain neurons. This is primarily attributed to distinctive properties exhibited by immature GABA receptors.Immature GABA-receptive neurons have a higher intracellular chloride concentration than mature neurons."More intracellular chloride is present in mature neurons than in immature GABA-receptive neurons" is the right response among the options given.Chloride ions are more prevalent in the intracellular environment of developing cortical neurons. One important element that plays a significant role in the excitatory response of GABA in developing neurons is this higher chloride concentration. Chloride ions enter these developing neurons when GABA attaches to its receptor. The membrane depolarizes as a result of this influx, increasing the likelihood that the neuron will produce an action potential. This increased chloride concentration is a key component of the excitatory response to GABA and separates immature neurons from their adult counterparts.Conclusion:In summary, the excitatory effect of GABA on immature cortical neurons can be attributed, in part, to the higher intracellular chloride concentration present in these developing neurons. This distinctive feature alters the response of GABA receptors, leading to an increased likelihood of neuronal excitation. Understanding this phenomenon sheds light on the complex interplay of molecular and cellular processes during neuronal development.So option c is correct.