The structure below is ibuprofin with weak acid pka 4.4 LOH Give the protonation state of ibuprofen in the stomach and draw the structure in (pH ~ 2)? Give the protonation state of ibuprofen in the bloodstream and draw the structure in (pH 7.3)? Blood is a buffer of bicarbonate and carbonic acid. Draw the curved arrow mechanism for the acid-base reaction that occurs between ibuprofen and bicarbonate in the bloodstream.
The structure below is ibuprofin with weak acid pka 4.4 LOH Give the protonation state of ibuprofen in the stomach and draw the structure in (pH ~ 2)? Give the protonation state of ibuprofen in the bloodstream and draw the structure in (pH 7.3)? Blood is a buffer of bicarbonate and carbonic acid. Draw the curved arrow mechanism for the acid-base reaction that occurs between ibuprofen and bicarbonate in the bloodstream.
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Chapter1: Chemical Foundations
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
Transcribed Image Text:The structure below is ibuprofin with weak acid pka 4.4
HO
Give the protonation state of ibuprofen in the stomach and draw the structure in (pH ~ 2)?
Give the protonation state of ibuprofen in the bloodstream and draw the structure in (pH 7.3)?
Blood is a buffer of bicarbonate and carbonic acid. Draw the curved arrow mechanism for the acid-base
reaction that occurs between ibuprofen and bicarbonate in the bloodstream.
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