The structural formula of propranolol, a common blood pressure medication, is shown below (left). To work, propranolol must pass through the cell membrane and enter the cell. How does propranolol do this? O Nonpolar rings engage in strong ID-ID IMFS with the membrane. O OH and NH groups engage in strong H-bonds with the membrane. O Nonpolar rings engage in strong ID-ID IMFS with other propranolol. O OH and NH groups engage in strong H-bonds with other propranolol. HC `CH reaction with HC CH lysosome .CH CH HC CH3 HC CH3 H2 HC, CH HC. CH CH3 `CH3 OH OH
The structural formula of propranolol, a common blood pressure medication, is shown below (left). To work, propranolol must pass through the cell membrane and enter the cell. How does propranolol do this? O Nonpolar rings engage in strong ID-ID IMFS with the membrane. O OH and NH groups engage in strong H-bonds with the membrane. O Nonpolar rings engage in strong ID-ID IMFS with other propranolol. O OH and NH groups engage in strong H-bonds with other propranolol. HC `CH reaction with HC CH lysosome .CH CH HC CH3 HC CH3 H2 HC, CH HC. CH CH3 `CH3 OH OH
Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Transcribed Image Text:The structural formula of propranolol, a common blood pressure
medication, is shown below (left). To work, propranolol must pass through
the cell membrane and enter the cell. How does propranolol do this?
O Nonpolar rings engage in strong ID-ID IMFS with the membrane.
O OH and NH groups engage in strong H-bonds with the membrane.
O Nonpolar rings engage in strong ID-ID IMFS with other propranolol.
O OH and NH groups engage in strong H-bonds with other propranolol.
T
IT
CH
reaction with
HC
HC
CH
lysosome
CH
CH
HC
CH3
HC
CH3
H2
HC.
CH
HC,
CH
CH3
CH3
OH
OH
Expert Solution
Step 1
Propranolol is a popular Beta-blocker used to treat high blood pressure and migraine. To reach the biological target, the drug needs to pass through the cell membrane and enter the cell. Hence it becomes important to study the binding of the drug to the lipid bilayer.
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