The sequence of crinia-angiotensin, an angiotensin II-like undecapeptide from the skin of the Australian frog, is determined. A single round of Edman degradation releases DNP-Ala. A second round sample of the peptide is then treated with chymotrypsin. Two fragments are released with the following amino acid composition: fragment 1: (H,P,F,V) and fragment 2 (A,D,R,G,P,I,Y). Next, a third sample of the peptide was treated with trypsin, which results in two fragments with the following amino acid compositions: fragment III (A,D,R,G,P) and fragment IV ( H,I,P,F,Y,V). Treatment of another sample with elastase yields three fragments, two of which are sequenced: fragment V (H-P-F) and fragment VI (A-P-G). What is the sequence of the undecapeptide?
The sequence of crinia-angiotensin, an angiotensin II-like undecapeptide from the skin of the Australian frog, is determined. A single round of Edman degradation releases DNP-Ala. A second round sample of the peptide is then treated with chymotrypsin. Two fragments are released with the following amino acid composition: fragment 1: (H,P,F,V) and fragment 2 (A,D,R,G,P,I,Y). Next, a third sample of the peptide was treated with trypsin, which results in two fragments with the following amino acid compositions: fragment III (A,D,R,G,P) and fragment IV ( H,I,P,F,Y,V). Treatment of another sample with elastase yields three fragments, two of which are sequenced: fragment V (H-P-F) and fragment VI (A-P-G). What is the sequence of the undecapeptide?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The sequence of crinia-angiotensin, an angiotensin II-like undecapeptide from the skin of the Australian frog, is determined. A single round of Edman degradation releases DNP-Ala. A second round sample of the peptide is then treated with chymotrypsin. Two fragments are released with the following amino acid composition: fragment 1: (H,P,F,V) and fragment 2 (A,D,R,G,P,I,Y). Next, a third sample of the peptide was treated with trypsin, which results in two fragments with the following amino acid compositions: fragment III (A,D,R,G,P) and fragment IV ( H,I,P,F,Y,V). Treatment of another sample with elastase yields three fragments, two of which are sequenced: fragment V (H-P-F) and fragment VI (A-P-G). What is the sequence of the undecapeptide?
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