the role of high density lipoprotein in chronic heart disease and familial hypercholesteremia

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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the role of high density lipoprotein in chronic heart disease and familial hypercholesteremia 

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Plasma high-density lipoproteins (HDLs), consist of the plasma lipoprotein particles with the density range of 1.063–1.210 g/mL. They are small lipid-protein complexes that are spherical in shape. 

HDL particles have an outer layer with phospholipid, free cholesterol, and various apolipoproteins (Apo). Thus, they cover a hydrophobic core with triglycerides and cholesterol esters. 

Apo I is made majorly in the liver and accounts for HDL's antiatherogenic effects. HDL protein sometimes contain bothe ApoI and ApoII. 

 

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