The recommended dosage of Cefradine is 20. mg/kg/day for children. If a child weighs 36 lb, what is the daily dose in mg for this child? If the stock vial of Cefradine is labelled 208 mg/mL, how many mL would be given in a daily dose? (1lb = 453.6 g) Show all your calculations

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The recommended dosage of Cefradine is 20. mg/kg/day for children. If a child weighs 36 lb, what is the daily dose in mg for this child? If the stock vial of Cefradine is labelled 208 mg/mL, how many mL would be given in a daily dose? (1lb = 453.6 g) Show all your calculations

CHEMICAL CONNECTIONS 1A
Drug Dosage and Body Mass
In many cases, drug dosages are prescribed on the ba-
sis of body mass. For example, the recommended dos-
age of a drug may be 3 mg of drug for each kilogram of
body weight. In this case, a 50 kg (110 lb) woman would
receive 150 mg and an 82 kg (180 lb) man would get
246 mg. This adjustment is especially important
for children, because a dose suitable for an adult will
generally be to0 much for a child, who has much less
body mass. For this reason, manufacturers package and
sell smaller doses of certain drugs, such as aspirin, for
Children's
Dosing Chart
Age (yr)
Dose (tsp)
Weight (Ib)
under 2 yr
ask a doctor
under 24 b
24-35 Ib
2-3 yr
1 tsp
4-5 yr
1 1/2 tsp
36-47 ib
children.
2 tsp
48-59 Ib
6-8 yr
Drug dosage may also vary with age. Occasionally,
when an elderly patient has an impaired kidney or liver
function, the clearance of a drug from the body is de-
layed, and the drug may stay in the body longer than
is normal. This persistence can cause dizziness, vertigo,
and migraine-like headaches, resulting in falls and bro-
ken bones. Such delayed clearance must be monitored
and the drug dosage adjusted accordingly.
9-10 yr
2 1/2 tsp
60-71 Ib
11 yr
3 tsp
72-95 Ib
Grape a Liquid
2-11
This package of Advil has a chart showing
the proper doses for children of a given
weight.
Charles D. Winters
Transcribed Image Text:CHEMICAL CONNECTIONS 1A Drug Dosage and Body Mass In many cases, drug dosages are prescribed on the ba- sis of body mass. For example, the recommended dos- age of a drug may be 3 mg of drug for each kilogram of body weight. In this case, a 50 kg (110 lb) woman would receive 150 mg and an 82 kg (180 lb) man would get 246 mg. This adjustment is especially important for children, because a dose suitable for an adult will generally be to0 much for a child, who has much less body mass. For this reason, manufacturers package and sell smaller doses of certain drugs, such as aspirin, for Children's Dosing Chart Age (yr) Dose (tsp) Weight (Ib) under 2 yr ask a doctor under 24 b 24-35 Ib 2-3 yr 1 tsp 4-5 yr 1 1/2 tsp 36-47 ib children. 2 tsp 48-59 Ib 6-8 yr Drug dosage may also vary with age. Occasionally, when an elderly patient has an impaired kidney or liver function, the clearance of a drug from the body is de- layed, and the drug may stay in the body longer than is normal. This persistence can cause dizziness, vertigo, and migraine-like headaches, resulting in falls and bro- ken bones. Such delayed clearance must be monitored and the drug dosage adjusted accordingly. 9-10 yr 2 1/2 tsp 60-71 Ib 11 yr 3 tsp 72-95 Ib Grape a Liquid 2-11 This package of Advil has a chart showing the proper doses for children of a given weight. Charles D. Winters
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