The reaction of an organic acid with an alcohol, inorganic solvent, to produce an ester and water is commonlydone in the pharmaceutical industry. This reactionis catalyzed by strong acid (usually H2SO4). A simpleexample is the reaction of acetic acid with ethyl alcoholto produce ethyl acetate and water: CH3COOH(solv) + CH3CH2OH(solv) ⇌ CH3COOCH2CH3(solv) + H2O(solv) where “(solv)” indicates that all reactants and products arein solution but not an aqueous solution. The equilibriumconstant for this reaction at 55 °C is 6.68. A pharmaceuticalchemist makes up 15.0 L of a solution that is initially0.275 M in acetic acid and 3.85 M in ethanol. At equilibrium,how many grams of ethyl acetate are formed?
The reaction of an organic acid with an alcohol, in
organic solvent, to produce an ester and water is commonly
done in the pharmaceutical industry. This reaction
is catalyzed by strong acid (usually H2SO4). A simple
example is the reaction of acetic acid with ethyl alcohol
to produce ethyl acetate and water:
CH3COOH(solv) + CH3CH2OH(solv) ⇌
CH3COOCH2CH3(solv) + H2O(solv)
where “(solv)” indicates that all reactants and products are
in solution but not an aqueous solution. The equilibrium
constant for this reaction at 55 °C is 6.68. A pharmaceutical
chemist makes up 15.0 L of a solution that is initially
0.275 M in acetic acid and 3.85 M in ethanol. At equilibrium,
how many grams of ethyl acetate are formed?
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