The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH? i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH)) ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH)) iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH)) iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH)) O Only i and iii are correct O Only i and ii are correct Only i, ii, and iii are correct O All four (i-iv) are correct O Only ii is correct O Only i is correct

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH?
i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH))
ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH))
iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH))
iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH))
Only i and iii are correct
Only i and ii are correct
Only i, ii, and iii are correct
All four (i-iv) are correct
Only ii is correct
Only i is correct
Transcribed Image Text:The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH? i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH)) ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH)) iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH)) iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH)) Only i and iii are correct Only i and ii are correct Only i, ii, and iii are correct All four (i-iv) are correct Only ii is correct Only i is correct
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