The protein hemoglobin (Hb) transports O2 in mammalianblood. Each Hb can bind 4 O2 molecules. The equilibriumconstant for the O2 binding reaction is higher infetal hemoglobin than in adult hemoglobin. In discussingprotein oxygen-binding capacity, biochemists use ameasure called the P50 value, defined as the partial pressureof oxygen at which 50% of the protein is saturated.Fetal hemoglobin has a P50 value of 19 torr, and adulthemoglobin has a P50 value of 26.8 torr. Use these data toestimate how much larger Kc is for the aqueous reaction4 O2(g) + Hb(aq) ⇌ [Hb(O2)4(aq)] in a fetus, comparedto Kc for the same reaction in an adult.
The protein hemoglobin (Hb) transports O2 in mammalianblood. Each Hb can bind 4 O2 molecules. The equilibriumconstant for the O2 binding reaction is higher infetal hemoglobin than in adult hemoglobin. In discussingprotein oxygen-binding capacity, biochemists use ameasure called the P50 value, defined as the partial pressureof oxygen at which 50% of the protein is saturated.Fetal hemoglobin has a P50 value of 19 torr, and adulthemoglobin has a P50 value of 26.8 torr. Use these data toestimate how much larger Kc is for the aqueous reaction4 O2(g) + Hb(aq) ⇌ [Hb(O2)4(aq)] in a fetus, comparedto Kc for the same reaction in an adult.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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The protein hemoglobin (Hb) transports O2 in mammalian
blood. Each Hb can bind 4 O2 molecules. The equilibrium
constant for the O2 binding reaction is higher in
fetal hemoglobin than in adult hemoglobin. In discussing
protein oxygen-binding capacity, biochemists use a
measure called the P50 value, defined as the partial pressure
of oxygen at which 50% of the protein is saturated.
Fetal hemoglobin has a P50 value of 19 torr, and adult
hemoglobin has a P50 value of 26.8 torr. Use these data to
estimate how much larger Kc is for the aqueous reaction
4 O2(g) + Hb(aq) ⇌ [Hb(O2)4(aq)] in a fetus, compared
to Kc for the same reaction in an adult.
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