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The picture below is of an amino acid called lysine: H₂N. NH₂ OH Download During a period of starvation in an otherwise healthy human, the citric acid cycle in hepatic tissue (liver cells) is depleted of a crucial intermediate due to the upregulation of gluconeogenesis. Answer the following questions: A) What is that crucial citric acid cycle intermediate that has been depleted due to the upregulaton of gluconeogenesis? B) After lysine catabolism, do you expect its products to form substrates for gluconeogenesis? If so, why? If not, why not? C) During periods of starvation, which end-products of lysine catabolism can be used as an energy source to maintain brain function? In your answer, clearly indicate which answer belongs to which part.

The picture below is of an amino acid called lysine: H₂N. NH₂ OH Download During a period of starvation in an otherwise healthy human, the citric acid cycle in hepatic tissue (liver cells) is depleted of a crucial intermediate due to the upregulation of gluconeogenesis. Answer the following questions: A) What is that crucial citric acid cycle intermediate that has been depleted due to the upregulaton of gluconeogenesis? B) After lysine catabolism, do you expect its products to form substrates for gluconeogenesis? If so, why? If not, why not? C) During periods of starvation, which end-products of lysine catabolism can be used as an energy source to maintain brain function? In your answer, clearly indicate which answer belongs to which part.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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The picture below is of an amino acid called lysine: H₂N. NH₂ OH Download During a period of starvation in an otherwise healthy human, the citric acid cycle in hepatic tissue (liver cells) is depleted of a crucial intermediate due to the upregulation of gluconeogenesis. Answer the following questions: A) What is that crucial citric acid cycle intermediate that has been depleted due to the upregulaton of gluconeogenesis? B) After lysine catabolism, do you expect its products to form substrates for gluconeogenesis? If so, why? If not, why not? C) During periods of starvation, which end-products of lysine catabolism can be used as an energy source to maintain brain function? In your answer, clearly indicate which answer belongs to which part.
Transcribed Image Text:The picture below is of an amino acid called lysine: H₂N. NH₂ OH Download During a period of starvation in an otherwise healthy human, the citric acid cycle in hepatic tissue (liver cells) is depleted of a crucial intermediate due to the upregulation of gluconeogenesis. Answer the following questions: A) What is that crucial citric acid cycle intermediate that has been depleted due to the upregulaton of gluconeogenesis? B) After lysine catabolism, do you expect its products to form substrates for gluconeogenesis? If so, why? If not, why not? C) During periods of starvation, which end-products of lysine catabolism can be used as an energy source to maintain brain function? In your answer, clearly indicate which answer belongs to which part.
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