The oxygen in water is primarily (99.8%) 1°0, but water enriched with the heavy isotope 180 is also available. When an aldehyde or ketone is dissolved in 180-enriched water, the isotopic label becomes incorporated into the carbonyl group. Explain. R2C=O+ H2O2 R2C=O+H20 where O = 180

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions
Section19.5: Nucleophilic Addition Of H2o: Hydration
Problem 8P: The oxygen in water is primarily (99.8) 16O, but water enriched with the heavy isotope 18O is also...
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The oxygen in water is primarily
(99.8%) 1°0, but water enriched with
the heavy isotope 180 is also available.
When an aldehyde or ketone is
dissolved in 180-enriched water, the
isotopic label becomes incorporated
into the carbonyl group. Explain.
R2C=O+ H2O2 R2C=O+H20 where O =
180
Transcribed Image Text:The oxygen in water is primarily (99.8%) 1°0, but water enriched with the heavy isotope 180 is also available. When an aldehyde or ketone is dissolved in 180-enriched water, the isotopic label becomes incorporated into the carbonyl group. Explain. R2C=O+ H2O2 R2C=O+H20 where O = 180
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