The Michaelis-Menten equation is often used to describe the kinetic characteristics of an enzyme-catalyzed reaction. Vmax [S] Km + [S] V = where u is the velocity, or rate, Vmax is the maximum velocity, Km is the Michaelis-Menten constant, and [S] is the substrate concentration. A graph of the Michaelis-Menten equation is a plot of a reaction's initial velocity (vo) at different substrate concentrations ([S]). First, move the line labeled Vmax to a position that represents the maximum velocity of the enzyme. Next, move the line labeled 1/2 Vmax to its correct position. Then, move the line labeled Km to its correct position. v (μM/min) 300 275 250 225 200 175 150 125 100 75 50 25 0 0 K m 10 20 30 V max 40 50 [S] (µM) 1/2 V max Michaelis Menten curve 60 70 80 90 100

Q: H,O2 (aq) + 2I + 21", (аg) (ад) 2H¿0 » +I2 aq)

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Q: The Km of an enzyme is 5.0 mM. Calculate the substrate concentration when this enzyme operates at…

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Q: An enzyme has a Km equal to 1.0 x 10-4 M (molar) for a certain substrate S. When [S] = 1.0 x 10-4 M,…

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Q: r an enzyme that displays Michaelis-Menton kinetics, what is the reaction velocity, V (as a…

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Q: An enzyme-catalyzed reaction follows zero-order kinetics. When the initial concentration of the…

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A: [S] = 0.1mMKI = 1.5 mMKm = 0.2 mM

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Q: Use the data below to determine the Michaelis-Menton constant [in mM] of a certain enzyme-catalyzed…

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Q: The Michaelis-Menten equation is often used to describe the kinetic characteristics of an…

A: According to the Michaelis-Menten equation the rate of an enzyme-catalyzed reaction is given by:…

Q: The enzyme-catalyzed reaction has the Michaelis-Menten constant KM=0.02 M. The reaction rate is v =…

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Q: Solve for the value of the rate constant, k. 00.78M/s=K[0.12] to the second order.

A: Rate constant,k= 54.17 L mol-1 s-1

Catalysis and Enzymatic Reactions

Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.

Lock And Key Model

The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.