The mean serum-creatinine level measured in 12 patients 24 hours after they received a newly proposed antibiotic was 1.2 mg/dL. Problem a) If the mean and standard deviation of serum creatinine in the general population are 1.0 and 0.4 mg/dL, respec-tively, then, using a significance level of .05, test whether the mean serum-creatinine level in this group is different from that of the general population. Problem b) What is the p-value for the test? Problem c)Suppose the sample standard deviation of serum creatinine in Problem a is 0.6 mg/dL. Assume that the standard deviation of serum creatinine is not known, and perform the hypothesis test in Problem a. Report a ­p-value.

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The mean serum-creatinine level measured in 12 patients
24 hours after they received a newly proposed antibiotic
was 1.2 mg/dL.
Problem a) If the mean and standard deviation of serum creatinine in the general population are 1.0 and 0.4 mg/dL, respec-tively, then, using a significance level of .05, test whether the mean serum-creatinine level in this group is different from that of the general population.
Problem b) What is the p-value for the test?

Problem c)Suppose the sample standard deviation of serum creatinine in Problem a is 0.6 mg/dL. Assume that the standard deviation of serum creatinine is not known, and perform the hypothesis test in Problem a. Report a ­p-value.
Problem d) Compute a two-sided 95% CI for the true mean
serum-creatinine level in Problem c.
Problem e) How does your answer to Problem d relate to your answer to Problem c.

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