105.The major products A and B in the following reaction sequence are(i) t-BuOK(2.2 equiv.)Mel(2.5 equival.), THFMeO(ii) NaBH4, MeOH(iii) AcCl, pyridine(iv) CF3CO₂H, Et3SiHCH₂Cl2(A)Li, t-BuOHliq. NH3, THF, -40°C(B)

Below the transformation are given in correct sequence

The major products A and B in the following reaction sequence are O MeO (i) t-BuOK(2.2 equiv.) Mel(2.5 equival.), THF (ii) NaBH4, MeOH (iii) AcCl, pyridine (iv) CF3CO₂H, Et3 SiH Li, t-BuOH liq. NH3, THF, -40°C (A). (B)

The major products A and B in the following reaction sequence are O MeO (i) t-BuOK(2.2 equiv.) Mel(2.5 equival.), THF (ii) NaBH4, MeOH (iii) AcCl, pyridine (iv) CF3CO₂H, Et3 SiH Li, t-BuOH liq. NH3, THF, -40°C (A). (B)

Chemistry by OpenStax (2015-05-04)

1st Edition

ISBN:9781938168390

Author:Klaus Theopold, Richard H Langley, Paul Flowers, William R. Robinson, Mark Blaser

Publisher:Klaus Theopold, Richard H Langley, Paul Flowers, William R. Robinson, Mark Blaser

Chapter20: Organic Chemistry

Section: Chapter Questions

Problem 28E: Acetylene is a very weak acid; however, it will react with moist silver(I) oxide and form water and...

See similar textbooks

Related questions

Q: 101. The major product formed in the following reaction sequence LAB Br (a) (b) (i) Br₂, H₂O (ii)…

A: Bromination followed by hydrolysis

Q: Select the major product of the following reaction. i. ii. HO2C. HO,C, -CO2H CO2H MeO2C. H3O*…

A: In this question, we want Identify the major Product. How we can identify, I will give details…

Q: 1. Predict the products or reagents as necessary for the following reactions. a. b. C. 12, NaOH…

A: Reaction-a is the haloform reaction. Compounds containing -COCH3 or -CH(OH)CH3 group react in alkali…

Q: 14. What reagent(s) will complete the following reaction? HO H20 Cu,O, Cu(NO3)2 H,O H2SO4 H2O NaOH…

A: This is an example of Sandmeyer reaction

Q: HO 2. Complete the following reactions by filling in any missing reactants, reagents or products. a)…

Q: What is the most proper major product for this reaction scheme? 2. 2. 1. 2CH,MgBr, THF 2. H D O A

A: Acid chlorides react with two equivalent of Grignard reagents to produce tertiary alcohols. Because…

Q: Provide the missing compounds and reagents in the reaction scheme. Identify reagent 5. он reagent 2…

Q: The best way to accomplish the following reaction is: CH3 CH3 (a) Hg(OAc)2, H₂O; NaBH4, HO™ (b) BH 3…

Q: 3. For the following reactions, predict the major products. C. d. O₂N CH₂ COOH Br CH₂ CH₂ Cl₂, FeCla…

A: As you have asked sub-multiple type questions more than three questions. So, according to the…

Q: 34. What is the major product of this reaction? Br₂/hv (A) (C) Br Br (B) (D) ~ 35. What reagents…

A: Alkanes react with bromine in the presence of light to form alkyl bromide. The reaction proceeds by…

Q: (1) MeO₂C CO₂Me 1. Reagents 2. Reaction Conditions 3. Mechanism CH3 0 OH

A: Note- Since the given question is a multiple question, hence I solved first question according to…

Q: 15) What is the product of the reaction series shown below? 15) NH2 NANO, HCI CUCN (1) CH,MgBr H;0,…

A: Product of series reaction:

Q: In each reaction box, place the best reagent and conditions from the list provided. 1) Br 2) 3) 4)…

Q: Identify a suitable reagent to carry out the transformation: OH CI The best conditions for the…

A: The given molecule contains an alcohol functional group and a chlorine substituent. This molecule is…

Q: The major product X in the reaction below is? H3C 0 а. O b. О с. O d. CH3 CH3 о-о HC SOH OCH3 1.…

A: Given,The reaction is:

Q: 6. What product(s) would you expect to obtain from the following reactions? (a) L NO₂ (c) CH3 H₂/Pd…

A: "Since you have asked multiple-subparts questions, we will solve the first-three subpart question…

Q: What is the missing reactant in step 2 of the following reaction sequence? (1) LDA (-78°C) (2) ? H*…

A: LDA is a sterically hindered strong base and it is used in the formation of the kinetic enolate ion.

Q: Provide the appropriate reagents or product in the following examples. 1. OH O Он 2. 1. m-CPBA, CHC…

A: Here we have to synthesise the following given compound from the starting material styrene by…

Q: Select the correct reaction.

A: Given are organic reactions. The starting compound is carboxylic acid..

Q: 1. For the following reaction give the arrow pushing mechanism. OH SH + O H₂N PyBOP = 1.2 equiv.…

Q: Choose the reagent(s) that would be most likely to complete this reaction. OsO4 (catalytic) NMO OH

Q: 16 What is X in the following reaction? * (i) X CH,-C=C-CH, (ii) H*/Zn CH,-C-C-CH, I| | HNO3 02 03…

A: The question is based on the concept of organic reactions. We have to identify the reagent.

Q: g) Predict starting materials G-J structure for Reaction 5 and 6.

A: This is McMurry reaction, we know that in this reaction two carbonyl group coupled together to…

Q: Identify the major product in the following reaction „CH. !CH.CH,MgBr II. H,O LO, H,SO,(conc.)…

Q: Q write mechansim Two reactions: (1) 1., H (1 equiv.) 2. a) LiAlH b) H2O work - up 3. H (final…

A: The objective of the question is to write the mechanism for the given reactions. However, the…

Q: Predict the product of each reaction. a) b) >==< HI (1 equiv.) 1. H₂, Lindlar's catalyst 2. RCO₂H 3.…

A: Organic Reactions are given.We have to identify the products formed in the reactions.

Q: Consider the reaction scheme below. e (i) H3COCHN CO₂Et A H₂N OH EtO OEt B C6H₁1 NO₂ base Ha…

A: To identify the reagent(s) and conditions A and the intermediate B in the reaction mixture.

Q: Select the best reagents for the reaction shown. O NaNH, 1.03: 2. H₂O O KMnO4 ? OH₂SO4, H₂O HO 1.…

A: The question relates the oxidation of alkyne through ozonolysis.Ozonolysis: The oxidative cleavage…

Q: How can you accomplish the reaction below? OH TsCl, pyridine H₂O, H₂SO4 H₂SO4 (conc.) 1. HI; 2.…

A: When alcohol reacts with protic acids, it tends to lose a molecule of water in order to form alkenes

Q: Provide the appropriate reagents or product in the following examples. OMe 2. 1.OsO, TBHP, H,O/THF…

A: 1. a.Heck reaction. b. Simmon Smith reaction. 2. a. Osmylation. b. Acetonide protection. C. Fridel…

Q: Which of the following reagents will result in the following reaction occurring? O H*/H₂O/Heat O H₂O…

A: Amides are the most stable carboxylic acid derivative and they can hydrolyze into carboxylic acid in…

Q: What is the product of the following sequence of reactions? CHO NACN H3O*, heat HCI OH OH .CO2H CN…

Q: ------ဂုံ-ပုံ CH₂OH CHÍNH, IV CH,NHCOCH,CH, (a) Name the reagent and conditions necessary for steps…

A: All of the reaction steps involved in the synthesis are electrophilic aromatic substitution…

Q: duct for the following reactions. 1. LDA, THF, -78 C; 2. TMSCI; 3. heat 1. BuLi, THF, -78 C; CHS 2.…

Q: In each reaction box, place the best reagent and conditions from the list provided. 1) Br 2) 3) DEET…

A: The reaction best reagents and conditions are listed below in attach image.

Q: NC. IV F Reactant-Reagent NO₂ OH CN fuming H₂SO4 NaOCH₂CH3 heat hot KMnO4 VI Product V

Q: 2. For the following three step conversion of A to B, the appropriate sequence of reactions is A OH…

A: PCC stands for pyridinium chlorochromate and is a reagent used in organic chemistry for the…

Concept explainers

NMR Spectroscopy

NMR stands for Nuclear Magnetic Resonance in which the study of different molecules is done based on the interaction of radiofrequency electromagnetic radiations with the nuclei of molecules placed in a strong magnetic field. A precise study of spectra of visible light and all bands of electromagnetic radiation is called spectroscopy.

Question

105.
The major products A and B in the following reaction sequence are
(i) t-BuOK(2.2 equiv.)
Mel(2.5 equival.), THF
MeO
(ii) NaBH4, MeOH
(iii) AcCl, pyridine
(iv) CF3CO₂H, Et3SiH
CH₂Cl2
(A)
Li, t-BuOH
liq. NH3, THF, -40°C
(B)

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step by step

Solved in 2 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Ll.48.
8. What is the product of the following reaction? CI O₂N- A) I B) II C) III D) IV -COOCH3 -COOCH3 H₂N- Fe, HCI -COOCH3 O₂N- a CI O₂N- IV -COOCH3 31 78 (0
The best way to accomplish the following reaction is: CH3 x CH3 (a) Hg(OAc)2, H₂O; NaBH4, HO™ (b) BH3 THF; H₂O₂, HO OH CH3 CH3 (c) H+, H₂O (d) 1. MCPBA; 2. H3O+
Which reagent(s) would complete the reaction?
Identify a suitable reagent to carry out the transformation: OH h CI The best conditions for the transformation are HCOOH,H*; 1. Mg; 2. CO₂, THF; 3. H+, H₂O O 1. NaCN; 2. KOH, H₂O, A; 3. H*, H₂O, A O 1. NaOH; 2. K₂ Cr₂O7, H₂O, H₂O4 OH COOH
1. Write the product(s) of the reactions. CH! (a). PhyP. Phop-Pt (b). oc fe OC CH:N2. oc-Mo-H oc co (c). CH (d). PPha
7. Reaction Scheme. NH₂ NH2 or two differnet methods (no same steps/reagents) C5H12N2 1. xs Mel, xs K2CO3 2. Ag2O, H₂O 3. heat Br2, xs NaOH, xs H₂O OHC 1.03 2. DMS CHO
What is the major product of the following reaction? 1. CH,I 2. Ag:0 3. heat A. B. C. D. O A O B O D MacBook Pro G Search or type URL 23 & 4 5 6 7 9 E R Y D F G H J K * CO
Q write mechansim Two reactions: (1) 1., H (1 equiv.) 2. a) LiAlH b) H2O work - up 3. H (final product only ) 1. 2. CH¸ MgBr 3. CH₂OH,H* Gwrite mechansim Two reactions: 0 ② CN 1. HO. OH H+ (1 equiv.) H 2. a) LiAlH4 b) H₂O work-up 3. H+ 1. HO (1 equiv.) H 2. CH3MgBr 3. CH3OH, H+ OH, H+ (final product only) OCH3 (±)
I. Give the major product for the following reactions. CH 1. LDA, THF, -78 C; 2. TMSCI; 3. heat CH 6. CH, 1. BuLi, THF, -78 C; 2. dil. HCI H,C 1. KH; CH, 2. dil. HCI HO CH, d. H,C. CH Zn Br Br
10. The best reagents for the following conversion is ? 30 (A) Cl2, CCl4 (C) CH2Cl2, Zn(Cu) (D) (B) CHCI 3, KOH HCI, (CH3)2CuLi
Please don't provide handwriting solution