The gene that determines ABO blood type and the gene that is mutated in Nail- Patella syndrome (NPS) are both located on chromosome 19 in humans. Nail-patella syndrome is dominant and completely penetrant. A B O AB B A A AB A O B 0 O A O AB B ABA a. From the pedigree of the family shown above, determine whether the gene determining ABO blood typ is linked to the NPS gene and, if so, calculate the map distance. Show your work b. The woman (indicated with an arrow) marries to a man with blood type B. Their first child is a boy of blood type O who is unaffected by NPS. What is the probability that their second child will be an unaffected girl with type B blood?
The gene that determines ABO blood type and the gene that is mutated in Nail- Patella syndrome (NPS) are both located on chromosome 19 in humans. Nail-patella syndrome is dominant and completely penetrant. A B O AB B A A AB A O B 0 O A O AB B ABA a. From the pedigree of the family shown above, determine whether the gene determining ABO blood typ is linked to the NPS gene and, if so, calculate the map distance. Show your work b. The woman (indicated with an arrow) marries to a man with blood type B. Their first child is a boy of blood type O who is unaffected by NPS. What is the probability that their second child will be an unaffected girl with type B blood?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Transcribed Image Text:The gene that determines ABO blood type and the gene that is mutated in Nail-
Patella syndrome (NPS) are both located on chromosome 19 in humans. Nail-patella syndrome is
dominant and completely penetrant.
A
O AB BA A AB A O
B
O A O AB B
A B A
a. From the pedigree of the family shown above, determine whether the gene determining ABO blood type
is linked to the NPS gene and, if so, calculate the map distance. Show your work
0
b. The woman (indicated with an arrow) marries to a man with blood type B. Their first child is a boy of
blood type O who is unaffected by NPS. What is the probability that their second child will be an
unaffected girl with type B blood?
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