The following steps were performed using enzyme cleavage of a peptide to determine its amino acid sequence. Step 1. FDNB yield DNB-Gly Step 2. Treatment with trypsin yield 3 fragments: Tyr-Leu-Asp-Arg; Gly-Ser-Ala-Lys; Trp-Gly-Ser-Met Step 3. Treatment with pepsin gave the same 3 peptide fragments.

Q: If the following truncated peptide represents the active domain of the COVID19’s S-protein…

A: Mutations are alterations in the DNA sequence of an organism. Small changes, such as adding or…

Q: You isolate a peptide that has the sequence Met-Val-Arg-Gln-Leu-Tyr-Lys-Trp Predict whether the…

A: Amino acids are compounds containing Carbon, hydrogen, oxygen and nitrogen and serve as monomers…

Q: Sickle cell anemia is caused by a point mutation in the β-globin chain of hemoglobin. Glutamic acid…

A: Introduction : Haemoglobin is a tetrameric proteinmade up of 2 alpha subunits and 2 beta subunits…

Q: (b) r , The following polypeptide sequence has three alpha helices and two B turns. Based on what we…

A: An amino group and an acid group-containing organic molecules are called Amino acids.…

Q: A solution of peptide of unknown sequence was divided into 2 samples. One sample was tre with…

A: Site specific proteases are enzymes that cleaves polypeptide chains only at specific sites i.e. at…

Q: the peptide (written N-terminal to C-terminal) represented by Ala-Ser-Ala-Tyr the same as the…

A: Ans. Yes, the polypeptide chain of amino acid will be Similarly in structure and function whether it…

Q: Sir Bong wanted to determine the a amino acide sequence og BONG. The summary of the analyses…

A: Since you have posted a question with multiple sub-parts, we will solve first three subparts for…

Q: Subjecting this peptide to trypsin would result in L-M-F-V-W-E-Q-A-P-S-P OA Lys and…

A: Trypsin is an enzyme that break peptide bond has a specific site of cleavage.

Q: How do you think incorporating b-homoserine into a peptide would affect the structure and/or…

A: Homoserine, is the product of a cyanogen bromide cleavage of a peptide by degradation of methionine.…

Q: Pompe disease is a rare genetic condition resulting from a deficiency of the protein…

A: Pompe disease is a genetic disorder that involves the accumulation of glycogen inside the cells.…

Q: How many amino acids are in KMT2D peptide sequence?

A: Introduction  Organic substances known as amino acids have both functional groups for amino and…

Q: In a folded protein, Glu116 is close in three-dimensional space to Lys224. The pKa of the carboxylic…

A: pKa is the pH at which a weak acid is 50% dissociated. Alternatively, pKa = -log Ka. In acid-base…

Q: Digestion of a peptide with trypsin generates two smaller peptide products: methionine-glycine and…

A: pepsin is a serine protease that cleaves the bond present in the C-terminal of amino acids Lysine…

Q: Pleasseee explain I’m confused…….

A: The charges of a peptide at different pH values depend on the ionization states of its amino acid…

Q: For each of the following sequences determine if they will most likely form an amphipathic α helix,…

A: Proteins are polymers of amino acids. The sequence of amino acids is governed by the sequences of…

Q: A peptide with 19 amino acid residues was digested with trypsin and generated the following…

A: The one letter code for different amino acids are :-  G - glycine I - isoleucine  R - arginine  S -…

Q: Consider the following coding 71 nucleotide DNA template sequence (It does not contain a…

A: In cell protein formed according to the sequence on mRNA. mRNA is formed from DNA sequence by the…

Q: Why would the mutation Ile -> Asp be likely to destabilize a protein? Why would the mutation Ile…

A: Mutations in proteins' amino acid sequences can have an impact on their stability. Long sequences of…

Q: Remembering that the amino acid side chains projecting from each polypeptide backbone in a β sheet…

A: Amongst secondary structures of polypeptide chains made of amino acids, β-sheets are a more spacious…

Q: Consider the following peptide sequence: Met-Ser-Val-Thr-Ile-Lys-Ala-Cys-Leu-Ser-lle-Tyr-Phe-Ser…

A: Structure of a protein or a peptide is described in four levels: primary, secondary, tertiary and…

Q: Consider the hypothetical serine protease in the image, which shows the specificity pockets. The S1…

A: Serine proteases are proteolytic enzymes that cleave peptide bonds. They are hydrolases that use a…

Q: This problem concerns a "typical" tyrosine residue found on the surface of a globular protein. a) If…

A: Tyrosine (Tyr or Y) is an aromatic amino acid that can be naturally produced by the body using…

Q: You are in the process of determining theamino acid sequence of a protein and must reconcile…

A: In the first trial, the protein has glycine at the amino terminal while asparagine at the carboxyl…

Q: Predict the amino acid sequence based on the conditions below. Use the one-letter abbreviation of…

A: Amino acids are building block of polypeptide chain. its alpha carbon contains carboxyl group, amine…

Q: Consider a mutation that results in a substitution of Cysteine (CYS) ) for Tyrosine (TYR) at…

A: Cysteine is a polar amino acid.  Cysteine is a triprotic acid with three ionizable functional…

Q: This problem concerns a "typical" tyrosine residue found on the surface of a globular protein. a)…

A: The side chain of tyrosine is ionizable. It has a pKa of 10.1. An ionizable group exists…

Q: you were given an unknown peptide. Explain in detail how you would determine the amino acid sequence…

A: The amino acids that form the protein are mostly L forms. The carboxyl group of amino acids in the…

Q: Given the R-groups in the peptide GLY-ASN-THR-LYS-HIS. It would most likely be: a)neither soluble…

A: Different amino acids have different R-groups. The R-groups can be polar or non-polar. Polar…

Q: A heptapeptide was found to have an amino acid composition of Asp, Leu, Lys, 2 Met, Phe and Tyr. (a)…

A: Proteins are important biomolecules in that it plays an important role in many biological functions.…

Q: Assume that the 3 polypeptide strands shown below form a parallel B-sheet. Select amino acids AA1,…

A: Beta sheet is one of type of secondary structure in which inter strand hydrogen bonds is formed…

Q: draw the structure of the tripeptife Pro-Ser-Cys as it would appear at physiological PH with its…

A: Amino acids can be polymerized to form chains. Peptide bond formation is a condensation reaction in…

Q: You are studying how your Lys-Val-Thr tripep de interacts with another pep de, which places an Asp…

A: Eventhough all ionizable groups have their characteristic pKa value, the pKa value of an ionizable…

Q: You are in the process of determining theamino acid sequence of a peptide. After trypsin digestion…

A: An amino acid is an organic molecule that is made up of a basic amino group, an acidic carboxyl…

Q: A polypeptide is subjected to the following digestion procedures and the fragments are sequenced.…

A: For this question we just need to to know sites of Trypsin and Cynogen Bromide at which they act and…

Q: Neurospora crassa can synthesize the amino acid arginine from a precursor as follows: precursor…

A: Culture media  A culture media or growth media is a mixture of nutrients and other materials which…

Q: pH @1 of Cys-His-Glu-Met-Ile-Ser-Thr-Arg-Tyr

A: Peptides are organic compounds made up of amino acids connected by peptide bonds. The specific…