The following questions relate to the resolution of (±)-a-phenylethylamine lab. Using the structures below, designate each chiral carbon in the salts as R or S. Are the salts enantiomers or diastereomers? Complete the reaction below assuming only the levorotatory salt is precipitated and isolated. Draw this final product in a correct 3-D orientation. NH2 ÇOOH NH3 COO NH3 COO H3C- H- OH H- CH3 H- NaOH H- OH но- H- но H- Но COOH COOH COOH racemic amine (+) tartaric acid salt salt
The following questions relate to the resolution of (±)-a-phenylethylamine lab. Using the structures below, designate each chiral carbon in the salts as R or S. Are the salts enantiomers or diastereomers? Complete the reaction below assuming only the levorotatory salt is precipitated and isolated. Draw this final product in a correct 3-D orientation. NH2 ÇOOH NH3 COO NH3 COO H3C- H- OH H- CH3 H- NaOH H- OH но- H- но H- Но COOH COOH COOH racemic amine (+) tartaric acid salt salt
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![### Resolution of (±)-α-Phenylethylamine Lab
The following instructions pertain to the resolution of (±)-α-phenylethylamine.
1. **Chiral Centers Designation:**
Using the structures provided below, designate each chiral carbon in the salts as R or S. Additionally, determine whether the salts are enantiomers or diastereomers.
2. **Reaction Completion:**
Complete the reaction below, assuming only the levorotatory salt is precipitated and isolated. Draw this final product in a correct 3-D orientation.
**Reagents and Reaction:**
- **Starting material:**
- Racemic amine (compound with an amine group (NH₂) and a benzene ring attached to a chiral carbon)
- **Reagent:**
- (+) Tartaric acid (contains two carboxylic acid groups and two hydroxyl groups)
1. **Formation of the Salts:**
- The racemic amine reacts with (+) tartaric acid to form two salts, which are presented in a 2-dimensional structural format.
- The structures of the two salts formed are:
- Salt 1: Contains an ammonium cation attached to a benzene ring and a tartrate anion.
- Salt 2: Similar in structure to Salt 1 but differs in the placement of groups around each chiral center.
2. **Reaction with NaOH:**
- The reaction proceeds with the addition of NaOH to isolate and form the final product.
### Structural Diagrams:
1. **Racemic Amine + Tartaric Acid:**
\[\text{racemic amine} + (+) \text{tartaric acid} \rightarrow \text{salt}\]
(Insert image of the reactants and salts here)
2. **Reaction with NaOH:**
\[\text{Salt} + \text{NaOH} \rightarrow \text{Final Product}\]
(Insert image of the final product here in the correct 3-D orientation)
### Understanding Chiral Centers:
- Chiral centers in organic molecules are carbon atoms that have four different groups attached to them. Each chiral carbon can be designated as either 'R' (Rectus, Latin for right) or 'S' (Sinister, Latin for left) based on its spatial configuration according to the Cahn](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F206206aa-1104-4dbc-9e08-21639f631eee%2F4b62df51-1bd3-4e81-9dd0-7fa59b8f5219%2Flt2ja6_processed.png&w=3840&q=75)
Transcribed Image Text:### Resolution of (±)-α-Phenylethylamine Lab
The following instructions pertain to the resolution of (±)-α-phenylethylamine.
1. **Chiral Centers Designation:**
Using the structures provided below, designate each chiral carbon in the salts as R or S. Additionally, determine whether the salts are enantiomers or diastereomers.
2. **Reaction Completion:**
Complete the reaction below, assuming only the levorotatory salt is precipitated and isolated. Draw this final product in a correct 3-D orientation.
**Reagents and Reaction:**
- **Starting material:**
- Racemic amine (compound with an amine group (NH₂) and a benzene ring attached to a chiral carbon)
- **Reagent:**
- (+) Tartaric acid (contains two carboxylic acid groups and two hydroxyl groups)
1. **Formation of the Salts:**
- The racemic amine reacts with (+) tartaric acid to form two salts, which are presented in a 2-dimensional structural format.
- The structures of the two salts formed are:
- Salt 1: Contains an ammonium cation attached to a benzene ring and a tartrate anion.
- Salt 2: Similar in structure to Salt 1 but differs in the placement of groups around each chiral center.
2. **Reaction with NaOH:**
- The reaction proceeds with the addition of NaOH to isolate and form the final product.
### Structural Diagrams:
1. **Racemic Amine + Tartaric Acid:**
\[\text{racemic amine} + (+) \text{tartaric acid} \rightarrow \text{salt}\]
(Insert image of the reactants and salts here)
2. **Reaction with NaOH:**
\[\text{Salt} + \text{NaOH} \rightarrow \text{Final Product}\]
(Insert image of the final product here in the correct 3-D orientation)
### Understanding Chiral Centers:
- Chiral centers in organic molecules are carbon atoms that have four different groups attached to them. Each chiral carbon can be designated as either 'R' (Rectus, Latin for right) or 'S' (Sinister, Latin for left) based on its spatial configuration according to the Cahn
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