The enolate of a ketone can be treated with an ester to give a diketone. Draw a mechanism for this Claisen-like reaction and explain why an acid source is required after the reaction is complete. For the mechanism, draw the curved arrows as needed. Include lone pairs and charges in your answer. Do not draw out any hydrogen explicitly in your products. Do not use abbreviations such as Me or Ph. 1) LDA DEt 2) 3) H,0

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
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Draw step 3 of the mechanism.
CH3
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Transcribed Image Text:Draw step 3 of the mechanism. CH3 Edit Drawing
The enolate of a ketone can be treated with an ester to give a diketone. Draw a mechanism for this Claisen-like reaction and explain
why an acid source is required after the reaction is complete.
For the mechanism, draw the curved arrows as needed. Include lone pairs and charges in your answer. Do not draw out any
hydrogen explicitly in your products. Do not use abbreviations such as Me or Ph.
1) LDA
2)
3) HO*
Step 1
Transcribed Image Text:The enolate of a ketone can be treated with an ester to give a diketone. Draw a mechanism for this Claisen-like reaction and explain why an acid source is required after the reaction is complete. For the mechanism, draw the curved arrows as needed. Include lone pairs and charges in your answer. Do not draw out any hydrogen explicitly in your products. Do not use abbreviations such as Me or Ph. 1) LDA 2) 3) HO* Step 1
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