The dominant Huntington disease allele causes severe neural/brain damage at approximately age 40. A female whose mother has Huntington disease wants to have a child with a male whose parents are normal. It is not known if the female has the disease. Keeping in mind that the disease allele is rare in the population, what is the probability that their firstborn will inherit the allele that causes Huntington disease? A) 25% B) 50% C) 75% D) 100%
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
The dominant Huntington disease allele causes severe neural/brain damage at approximately age 40. A female whose mother has Huntington disease wants to have a child with a male whose parents are normal. It is not known if the female has the disease. Keeping in mind that the disease allele is rare in the population, what is the probability that their firstborn will inherit the allele that causes Huntington disease?
A) 25%
B) 50%
C) 75%
D) 100%
E) 0%
Neurodegenerative diseases are a diverse category of conditions. They have a distinguishing trait of gradual degeneration in which the central and peripheral nervous system's structure and function are hindered. Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases are examples. Huntington's disease, for example, is an inheritable neurological disease that can be passed on from parent to child.
Huntington's disease is an autosomal dominant neurological illness that is passed down from one generation to the next. A child's offspring have a 50% risk of inheriting the condition from their parents. Early on in the course of the disease, a person suffering from it will exhibit symptoms such as forgetfulness, depression, falls, and so on.
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