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The data in the table below came from randomized controlled trials that tested the · effectiveness of Aspirin (versus placebo) in preventing death after a myocardial· infarction (MI). The data from these studies were collected for the purpose of conducting a meta-analysis for a systematic review on the effectiveness of Aspirin. · The purpose of a meta-analysis is to pool (combine) the data from multiple studies in order to provide an estimate of the treatment effect across the pooled studies. The labels in the table refer to the following: Study (study reference), dth_plac (number of oinants-that-diodin-thoplacobo-crow tot ploo-total-numbor.of.norticinontain.

The data in the table below came from randomized controlled trials that tested the · effectiveness of Aspirin (versus placebo) in preventing death after a myocardial· infarction (MI). The data from these studies were collected for the purpose of conducting a meta-analysis for a systematic review on the effectiveness of Aspirin. · The purpose of a meta-analysis is to pool (combine) the data from multiple studies in order to provide an estimate of the treatment effect across the pooled studies. The labels in the table refer to the following: Study (study reference), dth_plac (number of oinants-that-diodin-thoplacobo-crow tot ploo-total-numbor.of.norticinontain.

A First Course in Probability (10th Edition)
A First Course in Probability (10th Edition)
10th Edition
ISBN:9780134753119
Author:Sheldon Ross
Publisher:Sheldon Ross
Chapter1: Combinatorial Analysis
Section: Chapter Questions
Problem 1.1P: a. How many different 7-place license plates are possible if the first 2 places are for letters and...
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How to use the equation below to solve for part B of the question

χ2 Σ = (Observed – Expected)2 Expected
Transcribed Image Text:χ2 Σ = (Observed – Expected)2 Expected
The data in the table below came from randomized controlled trials that tested the effectiveness of Aspirin (versus placebo) in preventing death after a myocardial infarction (MI). The data from these studies were collected for the purpose of conducting a meta-analysis for a systematic review on the effectiveness of Aspirin. The purpose of a meta-analysis is to pool (combine) the data from multiple studies in order to provide an estimate of the treatment effect across the pooled studies. The labels in the table refer to the following: Study (study reference), dth_plac (number of participants that died in the placebo group), tot plac (total number of participants in the placebo group), dth_asp (number of participants that died in the aspirin-group), and tot asp (total number of participants in the aspirin group). Use the data in this table to answer the questions below the table.< Study Elwood_etal 1974 Coronary_1976 Breddin_etal_1979 Persantine 1980 Elwood Sweetman_1979 126 Aspirin 1980 dth_plac tot_plac dth_asp tot_asp ISIS2_1988 67 64 38 52 219 624 49 77 850 309 406 44 102 32 85 615 757 832 317 810 2257 346 2267 1720 8600 1570 8587 A. →Conduct the appropriate statistical test to determine whether the proportion that died. in the placebo group was greater than the proportion that died in the aspirin group for the ISIS2_1988-study. Assume a=0.05. Show all calculations. < B.→Conduct the appropriate statistical test to determine whether there is an association between treatment group (aspirin, placebo) and deaths (yes/no) in the Persantine_1980 study. Assume a=0.01. Show all calculations.
Transcribed Image Text:The data in the table below came from randomized controlled trials that tested the effectiveness of Aspirin (versus placebo) in preventing death after a myocardial infarction (MI). The data from these studies were collected for the purpose of conducting a meta-analysis for a systematic review on the effectiveness of Aspirin. The purpose of a meta-analysis is to pool (combine) the data from multiple studies in order to provide an estimate of the treatment effect across the pooled studies. The labels in the table refer to the following: Study (study reference), dth_plac (number of participants that died in the placebo group), tot plac (total number of participants in the placebo group), dth_asp (number of participants that died in the aspirin-group), and tot asp (total number of participants in the aspirin group). Use the data in this table to answer the questions below the table.< Study Elwood_etal 1974 Coronary_1976 Breddin_etal_1979 Persantine 1980 Elwood Sweetman_1979 126 Aspirin 1980 dth_plac tot_plac dth_asp tot_asp ISIS2_1988 67 64 38 52 219 624 49 77 850 309 406 44 102 32 85 615 757 832 317 810 2257 346 2267 1720 8600 1570 8587 A. →Conduct the appropriate statistical test to determine whether the proportion that died. in the placebo group was greater than the proportion that died in the aspirin group for the ISIS2_1988-study. Assume a=0.05. Show all calculations. < B.→Conduct the appropriate statistical test to determine whether there is an association between treatment group (aspirin, placebo) and deaths (yes/no) in the Persantine_1980 study. Assume a=0.01. Show all calculations.
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