The allele makeup of a population in different generations. 1 0.8 0.6 0.4 0.2 1 4 5 Generation Freq. of A1 (= p) -Freq. of A2 (= q) Population 2.
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A:
Q: Many genetic disorders, such as cystic fibrosis and sickle-cell disease are due to mutations in a…
A: Given: Frequency of 'aa' genotype = 36% To find: Frequency of 'a' allele =?
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A: Introduction Tay - Sachs is rare inherited neurological disorder .
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A: Genotypic frequency of bb = 160/1000 = 0.16 allele frequency of b (q) we know, q2 = 0.16 q = 0.4
Q: Genotype frequency of two alleles have been calculated to be p = .2 and q = .8 Is this population of…
A: C. Not enough information to calculate this.
Q: What is the percentage of people with light eyes in the population were the concentration of the…
A: According to hardy Weinberg p²+ 2pq +q² = 1 p+q = 1 q = 0.4 0.6² +(2×0.6×0.4) +0.4²
Q: If all copies of a given locus have the same allele throughout the population, the allele frequency…
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Q: The frequency of the recessive allele (r) in a population is equal to 0.70. What percentage of the…
A: = dominant homozygous frequency (AA) = heterozygous frequency (Aa) = recessive…
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- Ch. 14-3 Marfan syndrome (Section 13.5) ) is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the associated allele if one parent does not carry it and the other is heterozygous?Under what conditions does one expect a 1:1:1:1 ratio?Ch. 14-4 Duchenne muscular dystrophy, which is inherited in an X-linked recessive pattern, nearly always occurs in males. Explain why.
- Why B is wrong?Spherocytosis is an inherited blood disease in whichthe erythrocytes (red blood cells) are spherical insteadof biconcave. This condition can be inherited in adominant fashion, with ANK1 (the nonfunctional mutant allele) dominant to ANK1+. In people with spherocytosis, the spleen recognizes the spherical redblood cells as defective and removes them from thebloodstream, leading to anemia. The spleen in different people removes the spherical erythrocytes withdifferent efficiencies. Some people with sphericalerythrocytes suffer severe anemia and some mild anemia, yet others have spleens that function so poorly nosymptoms of anemia exist at all. When 2400 peoplewith the genotype ANK1 ANK1+ were examined, itwas found that all of them had spherical erythrocytes,2250 had anemia of varying severity, and 150 had nosymptoms. (Assume that ANK1 ANK1 homozygotesdo not exist.)a. Does this description of people with spherocytosisrepresent incomplete penetrance, variable expressivity, or both? Explain…Mention Mendelian laws and how they fit in with sickle cell anaemia Are there any advantages to having sickle cell anaemia?
- All the non-shaded individuals are wild type apart from III.1. III.1 has been proven to have the causative mutation for this Autosomal Dominant condition, but they exhibit no symptoms.What is the percentage level of penetrance for the condition in the diagram?Why B is correct?Ch. 13-5 Heterozygous individuals perpetuate some alleles that have lethal effects in homozygous individuals. A mutated allele (ML ) associated with taillessness in Manx cats (left) is an example. Cats homozygous for this allele (MLML ) typically die before birth due to severe spinal cord defects. In a case of incomplete dominance, cats heterozygous for the ML allele and the normal, unmutated allele (M) have a short, stumpy tail or none at all. Two MLM cats mate. What is the probability that any one of their surviving kittens will be heterozygous?
- Suppose two parents are healthy carriers of the sickle cell allele. The genotype of each parent is HbAHbS (HbAis the normal allele, and HbS is the sickle-cell allele).How likely is it for a child of these parents to have sickle cell anemia (HbSHbS)?The hemoglobin B gene (Hb) has a common allele (A) ofa SNP (rs334) that encodes the HbA form of (adult) hemoglobin and a rare allele (T ) that encodes the sicklingform of hemoglobin, HbS. Among 571 residents of a village in Nigeria, 440 were A/A and 129 were A/T, and 2were T/T individuals were observed. Use the χ2 test todetermine whether these observed genotypic frequencies fit Hardy–Weinberg expectations.9, 6 77 10 9I The following 5 population genetics questions refer to this introduction: "Tay-Sachs disease is inherited as an autosomal recessive, caused by the absence of hexosaminidase-A (Hex-A). Without Hex-A a lipid accumulates in cells, particularly in the brain, resulting in homozygous recessive individuals regressing in mental and physical function until death in early childhood. Heterozygotes have abnormal Hex-A activity but manifest no disease symptoms. In a large eastern European population, the frequency of Tay-Sachs disease is 3 percent. Using this information answer the following." a) If the population is assumed to be in Hardy-Weinberg equilibrium with respect to Tay-Sachs, what is the frequency of the allele that causes Tay-Sachs (answer in two decimal points [DP])? b) What would be the frequency of heterozygotes (answer in 2 DP)? Assessment Navigator c) Assuming no assortative mating, what is the probability of two heterozygotes mating (answer in 2DP)? 1 2 3 d) In…