that move a cell through the cycle when it meets the correct requirements. If the cell does not meet the requirements, negative regulation molecules will either try to repair the damage or signal for apoptosis. In order for a cell to move through the cycle, it must go through several checkpoints. The G₁ checkpoint makes sure that the cell has favorable conditions for division. The cell must have enough growth and energy reserves to proceed onto the next phase of the cycle. At this stage, DNA is also inspected for damage. DNA that is not suitable, or cannot be repaired, will not move through to the S phase to be replicated and will exit the cell cycle by entering the inactive Go phase. The cell encounters the next review at the end of the G₂ phase. The G₂ phase includes protein synthesis and another round of growth. The G₂ checkpoint assesses the size and protein reserves of the cell as well as the accuracy of the chromosome replication. If DNA is damaged, the cell tries to repair the damage before the beginning of mitotic division. The M checkpoint determines if all of the sister chromatids are properly attached to spindle microtubules and ready for separation. The model shows the checkpoints of the cell cycle. G₂ checkpoint (88) (88) ⓇE Mcheckpoint Mitosis Cytokinesis G₁ G.checkpoint G₂ The separated chromatids are pulled toward each pole of the cell. The cell first experiences growth. The cell synthesizes DNA in its nucleus. The cytoplasm of the cell divides to form two daughter cells. The cell is not dividing nor preparing to divide. The cell creates proteins and organizes for division. G₁ O 0 0 O O 。。。。 O O 。。。。。 。。。oo O O Mitosis 0 O O O O Cytokinesis O O O O O T O

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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that move a cell through the cycle when it meets the correct requirements. If the cell does not meet the requirements,
negative regulation molecules will either try to repair the damage or signal for apoptosis.
In order for a cell to move through the cycle, it must go through several checkpoints. The G₁ checkpoint makes sure that
the cell has favorable conditions for division. The cell must have enough growth and energy reserves to proceed onto the
next phase of the cycle. At this stage, DNA is also inspected for damage. DNA that is not suitable, or cannot be repaired,
will not move through to the S phase to be replicated and will exit the cell cycle by entering the inactive G₁ phase. The cell
encounters the next review at the end of the G₂ phase. The G₂ phase includes protein synthesis and another round of
growth. The G₂ checkpoint assesses the size and protein reserves of the cell as well as the accuracy of the chromosome
replication. If DNA is damaged, the cell tries to repair the damage before the beginning of mitotic division. The M
checkpoint determines if all of the sister chromatids are properly attached to spindle microtubules and ready for
separation.
The model shows the checkpoints of the cell cycle.
G₂ checkpoint
(88)
Mcheckpoint
Mitosis
Cytokinesis
G₁
G, checkpoint
G₂ (1)
The separated chromatids are pulled
toward each pole of the cell.
The cell first experiences growth.
The cell synthesizes DNA in its
nucleus.
The cytoplasm of the cell divides to
form two daughter cells.
The cell is not dividing nor preparing
to divide
The cell creates proteins and
organizes for division.
G₁
ooo
O
Go
O
G₂ Mitosis Cytokinesis
00
O
O
O
O
O
O
O
O
O
O
1
O
Transcribed Image Text:that move a cell through the cycle when it meets the correct requirements. If the cell does not meet the requirements, negative regulation molecules will either try to repair the damage or signal for apoptosis. In order for a cell to move through the cycle, it must go through several checkpoints. The G₁ checkpoint makes sure that the cell has favorable conditions for division. The cell must have enough growth and energy reserves to proceed onto the next phase of the cycle. At this stage, DNA is also inspected for damage. DNA that is not suitable, or cannot be repaired, will not move through to the S phase to be replicated and will exit the cell cycle by entering the inactive G₁ phase. The cell encounters the next review at the end of the G₂ phase. The G₂ phase includes protein synthesis and another round of growth. The G₂ checkpoint assesses the size and protein reserves of the cell as well as the accuracy of the chromosome replication. If DNA is damaged, the cell tries to repair the damage before the beginning of mitotic division. The M checkpoint determines if all of the sister chromatids are properly attached to spindle microtubules and ready for separation. The model shows the checkpoints of the cell cycle. G₂ checkpoint (88) Mcheckpoint Mitosis Cytokinesis G₁ G, checkpoint G₂ (1) The separated chromatids are pulled toward each pole of the cell. The cell first experiences growth. The cell synthesizes DNA in its nucleus. The cytoplasm of the cell divides to form two daughter cells. The cell is not dividing nor preparing to divide The cell creates proteins and organizes for division. G₁ ooo O Go O G₂ Mitosis Cytokinesis 00 O O O O O O O O O O 1 O
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