Table 1: Arterial blood gas concentration in patient Two hours after aspirin ingestion Ten hours after aspirin ingestion Normal values Partial Pressure CO2 26 mm Hg 19 mm Hg 35-45 mm Hg Partial Pressure O2 113 mm Hg 143 mm Hg 75-100 mm Hg Bicarbonate [HCO;] 18 mM 21 mM 22-26 mM pH 7.44 7.55 7.35-7.45 Blood salicylate concentration, mg/dL 57 117 4. It has been shown that aspirin acts directly on the nervous system to stimulate respiration. Thus, our patient is hyperventilating due to her aspirin overdose. a. Based on lab results from Table 1, what happens to the carbon dioxide and oxygen levels in the patient's blood during aspirin-induced hyperventilation? Explain. b. Explain how aspirin-induced hyperventilation causes the pH of the patient's blood to increase. (Hint: what acid/base pair is the blood's main buffering system?)

Biochemistry
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ISBN:9781319114671
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Chapter1: Biochemistry: An Evolving Science
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Table 1: Arterial blood gas concentration in patient
Two hours after aspirin
ingestion
Ten hours after aspirin
ingestion
Normal values
Partial Pressure CO2
26 mm Hg
19 mm Hg
35-45 mm Hg
Partial Pressure O2
113 mm Hg
143 mm Hg
75-100 mm Hg
Bicarbonate [HCO;]
18 mM
21 mM
22-26 mM
pH
7.44
7.55
7.35-7.45
Blood salicylate
concentration, mg/dL
57
117
Transcribed Image Text:Table 1: Arterial blood gas concentration in patient Two hours after aspirin ingestion Ten hours after aspirin ingestion Normal values Partial Pressure CO2 26 mm Hg 19 mm Hg 35-45 mm Hg Partial Pressure O2 113 mm Hg 143 mm Hg 75-100 mm Hg Bicarbonate [HCO;] 18 mM 21 mM 22-26 mM pH 7.44 7.55 7.35-7.45 Blood salicylate concentration, mg/dL 57 117
4. It has been shown that aspirin acts directly on the nervous system to stimulate respiration. Thus, our patient
is hyperventilating due to her aspirin overdose.
a. Based on lab results from Table 1, what happens to the carbon dioxide and oxygen levels in the patient's
blood during aspirin-induced hyperventilation? Explain.
b. Explain how aspirin-induced hyperventilation causes the pH of the patient's blood to increase. (Hint: what
acid/base pair is the blood's main buffering system?)
Transcribed Image Text:4. It has been shown that aspirin acts directly on the nervous system to stimulate respiration. Thus, our patient is hyperventilating due to her aspirin overdose. a. Based on lab results from Table 1, what happens to the carbon dioxide and oxygen levels in the patient's blood during aspirin-induced hyperventilation? Explain. b. Explain how aspirin-induced hyperventilation causes the pH of the patient's blood to increase. (Hint: what acid/base pair is the blood's main buffering system?)
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