Table 1: Arterial blood gas concentration in patient Two hours after aspirin ingestion Ten hours after aspirin ingestion Normal values Partial Pressure CO2 26 mm Hg 19 mm Hg 35-45 mm Hg Partial Pressure O2 113 mm Hg 143 mm Hg 75-100 mm Hg Bicarbonate [HCO;] 18 mM 21 mM 22-26 mM pH 7.44 7.55 7.35-7.45 Blood salicylate concentration, mg/dL 57 117 4. It has been shown that aspirin acts directly on the nervous system to stimulate respiration. Thus, our patient is hyperventilating due to her aspirin overdose. a. Based on lab results from Table 1, what happens to the carbon dioxide and oxygen levels in the patient's blood during aspirin-induced hyperventilation? Explain. b. Explain how aspirin-induced hyperventilation causes the pH of the patient's blood to increase. (Hint: what acid/base pair is the blood's main buffering system?)
Table 1: Arterial blood gas concentration in patient Two hours after aspirin ingestion Ten hours after aspirin ingestion Normal values Partial Pressure CO2 26 mm Hg 19 mm Hg 35-45 mm Hg Partial Pressure O2 113 mm Hg 143 mm Hg 75-100 mm Hg Bicarbonate [HCO;] 18 mM 21 mM 22-26 mM pH 7.44 7.55 7.35-7.45 Blood salicylate concentration, mg/dL 57 117 4. It has been shown that aspirin acts directly on the nervous system to stimulate respiration. Thus, our patient is hyperventilating due to her aspirin overdose. a. Based on lab results from Table 1, what happens to the carbon dioxide and oxygen levels in the patient's blood during aspirin-induced hyperventilation? Explain. b. Explain how aspirin-induced hyperventilation causes the pH of the patient's blood to increase. (Hint: what acid/base pair is the blood's main buffering system?)
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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