2:21 PM Sun May 21TOHstarting materialSYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting materialprovided along with alkanes of 4 carbons as your carbon source for the target. You may also use generalreagents, including protecting groups provided carbons in these reagents do not end up in the carbonframework of the final product.→ila26%target product+:011JsSYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting materialprovided along with any general reagents, protecting groups, sodium cyanide and alkanes of 3 carbons orfewer (organic reagents/protecting groups may have more than 6 carbons provided these carbons do notend up in the carbon framework of the final product).

Protecting groups are needed when two reactive groups are present in same compound. To achieve…

SYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting material provided along with alkanes of 4 carbons as your carbon source for the target. You may also use general reagents, including protecting groups provided carbons in these reagents do not end up in the carbon framework of the final product. ion OH starting material ila target product

SYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting material provided along with alkanes of 4 carbons as your carbon source for the target. You may also use general reagents, including protecting groups provided carbons in these reagents do not end up in the carbon framework of the final product. ion OH starting material ila target product

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.

Question

2:21 PM Sun May 21
T
OH
starting material
SYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting material
provided along with alkanes of 4 carbons as your carbon source for the target. You may also use general
reagents, including protecting groups provided carbons in these reagents do not end up in the carbon
framework of the final product.
→
ila
26%
target product
+:0
11
Js
SYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting material
provided along with any general reagents, protecting groups, sodium cyanide and alkanes of 3 carbons or
fewer (organic reagents/protecting groups may have more than 6 carbons provided these carbons do not
end up in the carbon framework of the final product).

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Step 1: Introduction:

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Step 2: Protection of ketone carbonyl group:

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Step 3: Oxidation of primary alcohol to aldehyde.

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Step 4: Reaction with grignard reagent

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Step 5: Deprotection of carbonyl group:

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