Synthesis of Ibuprofen-Part 2: 1. Some pain relievers including ibuprofen (MotrinⓇ) and naproxen (AleveⓇ) are "α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. F 2. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
Synthesis of Ibuprofen-Part 2: 1. Some pain relievers including ibuprofen (MotrinⓇ) and naproxen (AleveⓇ) are "α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. F 2. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Please answer in detail and show all your work, thank you! Synthesis of Ibuprofen-Part 2: Some pain relievers including ibuprofen (Motrin ® and naproxen (Aleve B are " α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
Transcribed Image Text:Synthesis of Ibuprofen-Part 2:
1. Some pain relievers including ibuprofen (MotrinⓇ) and naproxen (AleveⓇ) are "α-arylpropanoic acids." Look up the structure
of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make
flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis.
F
2. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What
reaction steps would need to change and how?
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