Synthesis of Acetylsalicylic acid (Aspirin) OH HO H* (H2SO4)* 5 drop HỌ CH3 H3C CH3 OH CH3 acetic anhydride 50`C salicylic acid acetylsalicylic acid acetic acid 15-20 min

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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I want to explain what happened in this reaction
Synthesis of Acetylsalicylic acid (Aspirin)
OH
HO
H*
LÖH
`CH3
(H2SO4)
5 drop
+
H3C
`CH3
OH
`CH3
acetic anhydride
50°C
acetic acid
salicylic acid
acetylsalicylic acid
15-20 min
m= 3g
Mw= 138 g/mol
m= 7 mL
Mw= 102 g/mol
Mw= 180 g/mol
Transcribed Image Text:Synthesis of Acetylsalicylic acid (Aspirin) OH HO H* LÖH `CH3 (H2SO4) 5 drop + H3C `CH3 OH `CH3 acetic anhydride 50°C acetic acid salicylic acid acetylsalicylic acid 15-20 min m= 3g Mw= 138 g/mol m= 7 mL Mw= 102 g/mol Mw= 180 g/mol
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