Synthesis a. Two possibilities for a Wittig synthesis of the compound below involve using: 1) cyclohexanone and ethyl bromide or 2) bromocyclohexane and ethanal. Is either route better, and if so, why is one superior? Be specific and explain where the difficulty lies for the inferior route CH3 b. Synthesize the following using 1-butene as your only source of carbon H₂C H₂C c. Synthesize the following compound using as carbon sources only benzene, toluene, benzaldehyde, acetic anhydride, and alcohols of four carbons or fewer. You can use any inorganic reagents and triphenyl phosphine OH
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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